The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Docosahexaenoate     (4Z,7Z,10Z,13Z,16Z,19Z)- docosa-4,7,10,13...

Synonyms: Cervonate, Doconexent, Doxonexent, Doconexento, Doconexentum, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Doconexent


Psychiatry related information on Doconexent


High impact information on Doconexent


Chemical compound and disease context of Doconexent


Biological context of Doconexent


Anatomical context of Doconexent


Associations of Doconexent with other chemical compounds


Gene context of Doconexent


Analytical, diagnostic and therapeutic context of Doconexent


  1. Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. Rose, D.P., Connolly, J.M., Rayburn, J., Coleman, M. J. Natl. Cancer Inst. (1995) [Pubmed]
  2. Cerebral norepinephrine depletion enhances recovery after brain ischemia. Busto, R., Harik, S.I., Yoshida, S., Scheinberg, P., Ginsberg, M.D. Ann. Neurol. (1985) [Pubmed]
  3. Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells. Narayanan, B.A., Narayanan, N.K., Simi, B., Reddy, B.S. Cancer Res. (2003) [Pubmed]
  4. Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation. Albino, A.P., Juan, G., Traganos, F., Reinhart, L., Connolly, J., Rose, D.P., Darzynkiewicz, Z. Cancer Res. (2000) [Pubmed]
  5. Docosahexaenoic acid reduces levodopa-induced dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine monkeys. Samadi, P., Grégoire, L., Rouillard, C., Bédard, P.J., Di Paolo, T., Lévesque, D. Ann. Neurol. (2006) [Pubmed]
  6. Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Calon, F., Lim, G.P., Yang, F., Morihara, T., Teter, B., Ubeda, O., Rostaing, P., Triller, A., Salem, N., Ashe, K.H., Frautschy, S.A., Cole, G.M. Neuron (2004) [Pubmed]
  7. Scotopic sensitivity in dyslexia and requirements for DHA supplementation. Greatrex, J.C., Drasdo, N., Dresser, K. Lancet (2000) [Pubmed]
  8. n-3 Polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Rao, J.S., Ertley, R.N., Lee, H.J., Demar, J.C., Arnold, J.T., Rapoport, S.I., Bazinet, R.P. Mol. Psychiatry (2007) [Pubmed]
  9. Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration. Johnson, E.J., Schaefer, E.J. Am. J. Clin. Nutr. (2006) [Pubmed]
  10. Dark adaptation, motor skills, docosahexaenoic acid, and dyslexia. Stordy, B.J. Am. J. Clin. Nutr. (2000) [Pubmed]
  11. Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors. Bazan, N.G. Trends Neurosci. (2006) [Pubmed]
  12. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. Serhan, C.N., Hong, S., Gronert, K., Colgan, S.P., Devchand, P.R., Mirick, G., Moussignac, R.L. J. Exp. Med. (2002) [Pubmed]
  13. Transcription of the murine iNOS gene is inhibited by docosahexaenoic acid, a major constituent of fetal and neonatal sera as well as fish oils. Khair-El-Din, T., Sicher, S.C., Vazquez, M.A., Chung, G.W., Stallworth, K.A., Kitamura, K., Miller, R.T., Lu, C.Y. J. Exp. Med. (1996) [Pubmed]
  14. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. Lukiw, W.J., Cui, J.G., Marcheselli, V.L., Bodker, M., Botkjaer, A., Gotlinger, K., Serhan, C.N., Bazan, N.G. J. Clin. Invest. (2005) [Pubmed]
  15. Arachidonic acid and docosahexaenoic acid are increased in human colorectal cancer. Neoptolemos, J.P., Husband, D., Imray, C., Rowley, S., Lawson, N. Gut (1991) [Pubmed]
  16. Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders. Martínez, M., Vázquez, E., García-Silva, M.T., Manzanares, J., Bertran, J.M., Castelló, F., Mougan, I. Am. J. Clin. Nutr. (2000) [Pubmed]
  17. A replication study of violent and nonviolent subjects: cerebrospinal fluid metabolites of serotonin and dopamine are predicted by plasma essential fatty acids. Hibbeln, J.R., Umhau, J.C., Linnoila, M., George, D.T., Ragan, P.W., Shoaf, S.E., Vaughan, M.R., Rawlings, R., Salem, N. Biol. Psychiatry (1998) [Pubmed]
  18. Familial adenomatous polyposis patients have high levels of arachidonic acid and docosahexaenoic acid and low levels of linoleic acid and alpha-linolenic acid in serum phospholipids. Almendingen, K., H??stmark, A.T., Fausa, O., Mosd??l, A., Aabakken, L., Vatn, M.H. Int. J. Cancer (2007) [Pubmed]
  19. Benefit of docosahexaenoic acid supplements to dark adaptation in dyslexics. Stordy, B.J. Lancet (1995) [Pubmed]
  20. Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? Rapoport, S.I., Bosetti, F. Arch. Gen. Psychiatry (2002) [Pubmed]
  21. Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Mukherjee, P.K., Marcheselli, V.L., Serhan, C.N., Bazan, N.G. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  22. Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. Houston, K.D., Copland, J.A., Broaddus, R.R., Gottardis, M.M., Fischer, S.M., Walker, C.L. Cancer Res. (2003) [Pubmed]
  23. Dietary omega-3 fatty acid deficiency and visual loss in infant rhesus monkeys. Neuringer, M., Connor, W.E., Van Petten, C., Barstad, L. J. Clin. Invest. (1984) [Pubmed]
  24. Long-term effects of dietary marine omega-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans. von Schacky, C., Fischer, S., Weber, P.C. J. Clin. Invest. (1985) [Pubmed]
  25. Influence of docosahexaenoic acid on cisplatin resistance in a human small cell lung carcinoma cell line. Timmer-Bosscha, H., Hospers, G.A., Meijer, C., Mulder, N.H., Muskiet, F.A., Martini, I.A., Uges, D.R., de Vries, E.G. J. Natl. Cancer Inst. (1989) [Pubmed]
  26. Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. Sperling, R.I., Benincaso, A.I., Knoell, C.T., Larkin, J.K., Austen, K.F., Robinson, D.R. J. Clin. Invest. (1993) [Pubmed]
  27. Antimalarial properties of n-3 and n-6 polyunsaturated fatty acids: in vitro effects on Plasmodium falciparum and in vivo effects on P. berghei. Kumaratilake, L.M., Robinson, B.S., Ferrante, A., Poulos, A. J. Clin. Invest. (1992) [Pubmed]
  28. Intravenous infusion of tridocosahexaenoyl-glycerol emulsion into rabbits. Effects on leukotriene B4/5 production and fatty acid composition of plasma and leukocytes. Nakamura, N., Hamazaki, T., Yamazaki, K., Taki, H., Kobayashi, M., Yazawa, K., Ibuki, F. J. Clin. Invest. (1993) [Pubmed]
  29. Prophylaxis of atherosclerosis with marine omega-3 fatty acids. A comprehensive strategy. von Schacky, C. Ann. Intern. Med. (1987) [Pubmed]
  30. Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3. Gao, L., Wang, J., Sekhar, K.R., Yin, H., Yared, N.F., Schneider, S.N., Sasi, S., Dalton, T.P., Anderson, M.E., Chan, J.Y., Morrow, J.D., Freeman, M.L. J. Biol. Chem. (2007) [Pubmed]
  31. The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts. Diaz, O., Berquand, A., Dubois, M., Di Agostino, S., Sette, C., Bourgoin, S., Lagarde, M., Nemoz, G., Prigent, A.F. J. Biol. Chem. (2002) [Pubmed]
  32. Nutritional effects on host response to lung infections with mucoid Pseudomonas aeruginosa in mice. van Heeckeren, A.M., Schluchter, M., Xue, L., Alvarez, J., Freedman, S., St George, J., Davis, P.B. Infect. Immun. (2004) [Pubmed]
  33. Docosahexaenoic acid prevents apoptosis of retina photoreceptors by activating the ERK/MAPK pathway. German, O.L., Insua, M.F., Gentili, C., Rotstein, N.P., Politi, L.E. J. Neurochem. (2006) [Pubmed]
  34. Docosahexaenoic acid attenuates mycotoxin-induced immunoglobulin a nephropathy, interleukin-6 transcription, and mitogen-activated protein kinase phosphorylation in mice. Jia, Q., Zhou, H.R., Bennink, M., Pestka, J.J. J. Nutr. (2004) [Pubmed]
  35. The effect of docosahexaenoic acid on aggression in young adults. A placebo-controlled double-blind study. Hamazaki, T., Sawazaki, S., Itomura, M., Asaoka, E., Nagao, Y., Nishimura, N., Yazawa, K., Kuwamori, T., Kobayashi, M. J. Clin. Invest. (1996) [Pubmed]
  36. Double-blind, randomized, controlled trial of fish oil supplements in prevention of recurrence of stenosis after coronary angioplasty. Bairati, I., Roy, L., Meyer, F. Circulation (1992) [Pubmed]
  37. Docosahexaenoic acid utilization during rod photoreceptor cell renewal. Gordon, W.C., Bazan, N.G. J. Neurosci. (1990) [Pubmed]
  38. Docosahexaenoic acid ameliorates murine ischemic acute renal failure and prevents increases in mRNA abundance for both TNF-alpha and inducible nitric oxide synthase. Kielar, M.L., Jeyarajah, D.R., Zhou, X.J., Lu, C.Y. J. Am. Soc. Nephrol. (2003) [Pubmed]
WikiGenes - Universities