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Gene Review

Wnt5b  -  wingless-type MMTV integration site family...

Mus musculus

Synonyms: AW545702, Protein Wnt-5b, Wnt-5b
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Disease relevance of Wnt5b

  • The cells were smaller and grew to a higher density than cells containing a control retrovirus or cells expressing Wnt-4 or Wnt-5b [1].

High impact information on Wnt5b


Biological context of Wnt5b


Anatomical context of Wnt5b


Regulatory relationships of Wnt5b


Other interactions of Wnt5b


  1. Alterations of the growth characteristics of the fibroblast cell line C3H 10T1/2 by members of the Wnt gene family. Bradbury, J.M., Niemeyer, C.C., Dale, T.C., Edwards, P.A. Oncogene (1994) [Pubmed]
  2. Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes. Kanazawa, A., Tsukada, S., Sekine, A., Tsunoda, T., Takahashi, A., Kashiwagi, A., Tanaka, Y., Babazono, T., Matsuda, M., Kaku, K., Iwamoto, Y., Kawamori, R., Kikkawa, R., Nakamura, Y., Maeda, S. Am. J. Hum. Genet. (2004) [Pubmed]
  3. Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation. Yang, Y., Topol, L., Lee, H., Wu, J. Development (2003) [Pubmed]
  4. Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Vertino, A.M., Taylor-Jones, J.M., Longo, K.A., Bearden, E.D., Lane, T.F., McGehee, R.E., MacDougald, O.A., Peterson, C.A. Mol. Biol. Cell (2005) [Pubmed]
  5. Wnt5b partially inhibits canonical Wnt/beta-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes. Kanazawa, A., Tsukada, S., Kamiyama, M., Yanagimoto, T., Nakajima, M., Maeda, S. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
  6. Comparative genomics on Wnt5a and Wnt5b genes. Katoh, M., Katoh, M. Int. J. Mol. Med. (2005) [Pubmed]
  7. Expression patterns of Wnt genes in mouse gut development. Lickert, H., Kispert, A., Kutsch, S., Kemler, R. Mech. Dev. (2001) [Pubmed]
  8. Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland. Weber-Hall, S.J., Phippard, D.J., Niemeyer, C.C., Dale, T.C. Differentiation (1994) [Pubmed]
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