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Gene Review

Trerf1  -  transcriptional regulating factor 1

Mus musculus

Synonyms: 9430096I18Rik, AI429294, B830015H24, RAPA, Transcriptional-regulating factor 1, ...
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Disease relevance of Trerf1


High impact information on Trerf1

  • The effects of cyclosporine (CsA), sirolimus (RAPA), and/or brequinar (BQR) were examined in a vascularized heterotopic heart transplant model in mice [3].
  • The combination of 2.5 mg/kg CsA with 0.05 mg/kg RAPA extended graft survival to 18.2 +/- 2.9 d (P < 0.01), and 5.0 mg/kg CsA with 0.1 mg/kg RAPA prolonged survival to 23.0 +/- 9.0 d (P < 0.01) [3].
  • The cDNA clone reported here, therefore, represents a novel pollen allergen of Brassica rapa [4].
  • A polyclonal antiserum was raised against the extracellular pollen proteins of Brassica rapa and used for screening the expression cDNA libraries made from immature anthers [4].
  • When Dex (0.1 mg/kg, s.c.) was injected 6 hr before the assay, Dex alone, TGF-beta 1 +/- Dex, FK506 (10 mg/kg, oral) +/- Dex, cyclosporin (CsA, 30 mg/kg, oral) +/- Dex, rapamycin (Rapa, 10 mg/kg, i.p.) +/- Dex, deoxyspergualin (DSP, 10 mg/kg, i.p.) +/- Dex, did not suppress the edemata (less than 11%) [1].

Analytical, diagnostic and therapeutic context of Trerf1


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