Gene Review:
PADI4 - peptidyl arginine deiminase, type IV
Homo sapiens
Synonyms:
HL-60 PAD, PAD, PAD4, PADI5, PDI4, ...
- PADI4 gene in multiple sclerosis: a family-based association study. Tommasi, C., Petit-Teixeira, E., Cournu-Rebeix, I., Caponi, L., Pierlot, C., Fontaine, B., Cornelis, F., Migliorini, P. J. Neuroimmunol. (2006)
- Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis. Barton, A., Bowes, J., Eyre, S., Symmons, D., Worthington, J., Silman, A. Ann. Rheum. Dis. (2005)
- Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation. Foulquier, C., Sebbag, M., Clavel, C., Chapuy-Regaud, S., Al Badine, R., Méchin, M.C., Vincent, C., Nachat, R., Yamada, M., Takahara, H., Simon, M., Guerrin, M., Serre, G. Arthritis Rheum. (2007)
- Histone deimination antagonizes arginine methylation. Cuthbert, G.L., Daujat, S., Snowden, A.W., Erdjument-Bromage, H., Hagiwara, T., Yamada, M., Schneider, R., Gregory, P.D., Tempst, P., Bannister, A.J., Kouzarides, T. Cell (2004)
- Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Suzuki, A., Yamada, R., Chang, X., Tokuhiro, S., Sawada, T., Suzuki, M., Nagasaki, M., Nakayama-Hamada, M., Kawaida, R., Ono, M., Ohtsuki, M., Furukawa, H., Yoshino, S., Yukioka, M., Tohma, S., Matsubara, T., Wakitani, S., Teshima, R., Nishioka, Y., Sekine, A., Iida, A., Takahashi, A., Tsunoda, T., Nakamura, Y., Yamamoto, K. Nat. Genet. (2003)
- Association between PADI4 and rheumatoid arthritis: a replication study. Ikari, K., Kuwahara, M., Nakamura, T., Momohara, S., Hara, M., Yamanaka, H., Tomatsu, T., Kamatani, N. Arthritis Rheum. (2005)
- A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans. Kang, C.P., Lee, H.S., Ju, H., Cho, H., Kang, C., Bae, S.C. Arthritis Rheum. (2006)
- Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis. Chang, X., Yamada, R., Suzuki, A., Sawada, T., Yoshino, S., Tokuhiro, S., Yamamoto, K. Rheumatology (Oxford, England) (2005)
- Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study. Hoppe, B., Häupl, T., Gruber, R., Kiesewetter, H., Burmester, G.R., Salama, A., Dörner, T. Arthritis Res. Ther. (2006)
- Overexpression of peptidylarginine deiminase IV features in apoptosis of haematopoietic cells. Liu, G.Y., Liao, Y.F., Chang, W.H., Liu, C.C., Hsieh, M.C., Hsu, P.C., Tsay, G.J., Hung, H.C. Apoptosis (2006)
- Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3). Nakashima, K., Hagiwara, T., Ishigami, A., Nagata, S., Asaga, H., Kuramoto, M., Senshu, T., Yamada, M. J. Biol. Chem. (1999)
- Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alpha-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1. Dong, S., Zhang, Z., Takahara, H. Mol. Endocrinol. (2007)
- Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Plenge, R.M., Padyukov, L., Remmers, E.F., Purcell, S., Lee, A.T., Karlson, E.W., Wolfe, F., Kastner, D.L., Alfredsson, L., Altshuler, D., Gregersen, P.K., Klareskog, L., Rioux, J.D. Am. J. Hum. Genet. (2005)
- Comparison of enzymatic properties between hPADI2 and hPADI4. Nakayama-Hamada, M., Suzuki, A., Kubota, K., Takazawa, T., Ohsaka, M., Kawaida, R., Ono, M., Kasuya, A., Furukawa, H., Yamada, R., Yamamoto, K. Biochem. Biophys. Res. Commun. (2005)
- Peptidylarginine deiminase 4 (PADI4) identified as a conformation-dependent autoantigen in rheumatoid arthritis. Takizawa, Y., Sawada, T., Suzuki, A., Yamada, R., Inoue, T., Yamamoto, K. Scand. J. Rheumatol. (2005)
- Genetic and genomic studies of PADI4 in rheumatoid arthritis. Harney, S.M., Meisel, C., Sims, A.M., Woon, P.Y., Wordsworth, B.P., Brown, M.A. Rheumatology (Oxford, England) (2005)