High impact information on Rnh1

• A bifid peak observed in the 16-15 Se region was shown to be an artifact caused by the ribonuclease inhibitor, naphthalene disulfonate [1].
• Characterization and use of the potent ribonuclease inhibitor aurintricarboxylic acid for the isolation of RNA from animal tissues [2].
• Alkaline ribonuclease and ribonuclease inhibitor in mammary gland during the lactation cycle and in the R3230AC mammary tumour [3].
• Addition of RNasin prior to heating cytosol in the absence of molybdate did not prevent the receptor from dissociating to the 5.2-nm form, suggesting that an endogenous RNase is not involved in the transformation process [4].
• Oestrogen-induced changes in the relative concentrations of ribonuclease and ribonuclease inhibitor in rat uterus [5].

Biological context of Rnh1

• A cDNA clone encoding ribonuclease inhibitor was isolated from a rat lung cDNA library [6].
• cDNA cloning and sequence of rat ribonuclease inhibitor, and tissue distribution of the mRNA [6].

Anatomical context of Rnh1

• Ribonuclease in the "nuclei fraction" was stimulated variably by the sulfhydryl blocker N-ethylmaleimide indicating that a proportion was bound to the endogenous ribonuclease inhibitor present in these ganglia [7].
• 4. Age, weight and particularly food restriction caused tissue-specific alterations of ribonuclease and ribonuclease inhibitor concentrations in liver, kidney, oesophagus, testis and thymus [8].

Associations of Rnh1 with chemical compounds

• On the similarity between ribonuclease inhibitor and beta-estradiol receptor protein [9].
• Effect of aging, castration, and testosterone administration on ribonuclease and ribonuclease-inhibitor activities in the prostate of rats [10].
• The enzyme was inhibited by p-chloromercuribenzoate and poly(G), but not by rat-liver ribonuclease-inhibitor and anti-RNase A serum [11].

Analytical, diagnostic and therapeutic context of Rnh1

• The 8.3-nm receptor form was converted to the 7.1-nm receptor form after treatment by ribonuclease A in the presence of molybdate and this effect was dose-dependent, being completely prevented by placental ribonuclease inhibitor (RNasin) [4].

References