Gene Review:
UL52 - helicase-primase primase subunit
Human herpesvirus 1
- Structures of herpes simplex virus type 1 genes required for replication of virus DNA. McGeoch, D.J., Dalrymple, M.A., Dolan, A., McNab, D., Perry, L.J., Taylor, P., Challberg, M.D. J. Virol. (1988)
- The UL5 and UL52 subunits of the herpes simplex virus type 1 helicase-primase subcomplex exhibit a complex interdependence for DNA binding. Biswas, N., Weller, S.K. J. Biol. Chem. (2001)
- An intertypic herpes simplex virus helicase-primase complex associated with a defect in neurovirulence has reduced primase activity. Barrera, I., Bloom, D., Challberg, M. J. Virol. (1998)
- Helicase-primase complex of herpes simplex virus type 1: a mutation in the UL52 subunit abolishes primase activity. Klinedinst, D.K., Challberg, M.D. J. Virol. (1994)
- The UL8 subunit of the herpes simplex virus type-1 DNA helicase-primase optimizes utilization of DNA templates covered by the homologous single-strand DNA-binding protein ICP8. Tanguy Le Gac, N., Villani, G., Hoffmann, J.S., Boehmer, P.E. J. Biol. Chem. (1996)
- Mutations in the putative zinc-binding motif of UL52 demonstrate a complex interdependence between the UL5 and UL52 subunits of the human herpes simplex virus type 1 helicase/primase complex. Chen, Y., Carrington-Lawrence, S.D., Bai, P., Weller, S.K. J. Virol. (2005)
- The herpes simplex virus type 1 UL8 protein influences the intracellular localization of the UL52 but not the ICP8 or POL replication proteins in virus-infected cells. Marsden, H.S., Cross, A.M., Francis, G.J., Patel, A.H., MacEachran, K., Murphy, M., McVey, G., Haydon, D., Abbotts, A., Stow, N.D. J. Gen. Virol. (1996)
- The two helicases of herpes simplex virus type 1 (HSV-1). Chattopadhyay, S., Chen, Y., Weller, S.K. Front. Biosci. (2006)
- Deletion mutants of the herpes simplex virus type 1 UL8 protein: effect on DNA synthesis and ability to interact with and influence the intracellular localization of the UL5 and UL52 proteins. Barnard, E.C., Brown, G., Stow, N.D. Virology (1997)