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Gene Review

Ccl20  -  chemokine (C-C motif) ligand 20

Rattus norvegicus

Synonyms: Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Liver and activation-regulated chemokine, ...
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Disease relevance of Ccl20


High impact information on Ccl20

  • Furthermore, at similar time points, BIMO treatment reduced intragraft expression of P-selectin glycoprotein ligand-1, CX(3)CL1, CCL19, CCL20, and CCL2 [4].
  • Freeze-thaw and cell lysis experiments, along with actinomycin D studies, suggested that CCL20 and TNF-alpha are synthesized in response to PAMP stimulation [1].
  • CCL20/macrophage inflammatory protein 3alpha and tumor necrosis factor alpha production by primary uterine epithelial cells in response to treatment with lipopolysaccharide or Pam3Cys [1].

Biological context of Ccl20

  • Both apical and basolateral secretion of CCL20 and TNF-alpha increased in response to PAMPs, but treatments had no effect on cell viability and integrity, as measured by transepithelial resistance [1].

Anatomical context of Ccl20


Associations of Ccl20 with chemical compounds


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