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Gene Review

CRISP2  -  cysteine-rich secretory protein 2

Bos taurus

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High impact information on TPX1


Biological context of TPX1


Anatomical context of TPX1


Other interactions of TPX1


Analytical, diagnostic and therapeutic context of TPX1

  • Northern blot analyses of SubH2Bv mRNA expression showed that it is testis-specific and is also present in murid testes [10].
  • Sequence analysis of 5 clones, which spans 23% (458,738 bp) of the region, and extensive gene scanning along the entire region revealed that the region is extraordinarily scarce in genes, but we identified one ubiquitously expressed novel gene and one testis-specific gene fragment [11].


  1. An evolutionarily conserved germ cell-specific hnRNP is encoded by a retrotransposed gene. Elliott, D.J., Venables, J.P., Newton, C.S., Lawson, D., Boyle, S., Eperon, I.C., Cooke, H.J. Hum. Mol. Genet. (2000) [Pubmed]
  2. A novel 205-kilodalton testis-specific serine/threonine protein kinase associated with microtubules of the spermatid manchette. Walden, P.D., Cowan, N.J. Mol. Cell. Biol. (1993) [Pubmed]
  3. Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice. Song, W.C., Moore, R., McLachlan, J.A., Negishi, M. Endocrinology (1995) [Pubmed]
  4. Tspy is nonfunctional in the Mongolian gerbil but functional in the Syrian hamster. Karwacki, V., Kovac, J., Mauceri, G., Backhaus, A., Föhse, L., Schmidtke, J., Schubert, S. Genomics (2006) [Pubmed]
  5. Organization and concerted evolution of the ampliconic Y-chromosomal TSPY genes from cattle. Verkaar, E.L., Zijlstra, C., van 't Veld, E.M., Boutaga, K., van Boxtel, D.C., Lenstra, J.A. Genomics (2004) [Pubmed]
  6. Conserved Y-chromosomal location of TSPY in Bovidae. Vogel, T., Borgmann, S., Dechend, F., Hecht, W., Schmidtke, J. Chromosome Res. (1997) [Pubmed]
  7. Cloning and characterization of complementary and genomic DNAs encoding the epsilon-subunit of rat translation initiation factor-2B. Flowers, K.M., Mellor, H., Matts, R.L., Kimball, S.R., Jefferson, L.S. Biochim. Biophys. Acta (1996) [Pubmed]
  8. Sperm PP1gamma2 is regulated by a homologue of the yeast protein phosphatase binding protein sds22. Huang, Z., Khatra, B., Bollen, M., Carr, D.W., Vijayaraghavan, S. Biol. Reprod. (2002) [Pubmed]
  9. Cloning and sequencing of cDNA encoding for the testis-specific fox (Vulpes vulpes) sperm polypeptide Vb of the cytochrome C oxidase. Verdier, Y., Farré, G., Rouet, N., Kele, Z., Janáky, T., Boué, F. J. Androl. (2005) [Pubmed]
  10. The major subacrosomal occupant of bull spermatozoa is a novel histone H2B variant associated with the forming acrosome during spermiogenesis. Aul, R.B., Oko, R.J. Dev. Biol. (2002) [Pubmed]
  11. A 2-Mb sequence-ready contig map and a novel immunoglobulin superfamily gene IGSF4 in the LOH region of chromosome 11q23.2. Gomyo, H., Arai, Y., Tanigami, A., Murakami, Y., Hattori, M., Hosoda, F., Arai, K., Aikawa, Y., Tsuda, H., Hirohashi, S., Asakawa, S., Shimizu, N., Soeda, E., Sakaki, Y., Ohki, M. Genomics (1999) [Pubmed]
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