Disease relevance of Muridae

• The murid filaria Monanema martini: a model for onchocerciasis. Part I. Description of lesions [1].

High impact information on Muridae

• We report here the cloning, developmental expression, and location of murid Sptrx-2 [2].
• Cloning and developmental analysis of murid spermatid-specific thioredoxin-2 (SPTRX-2), a novel sperm fibrous sheath protein and autoantigen [2].
• T-cell responses to the M3 immune evasion protein of murid gammaherpesvirus 68 are partially protective and induced with lytic antigen kinetics [3].
• Infection of mice by murid herpesvirus 4 strain 68 (MHV-68) is an established animal model for gammaherpesvirus pathogenesis and expresses an analogous glycoprotein, gp150 [4].
• This suggests that nuclear subunits interacting with cytochrome b face the greatest constraints in the coevolution of murid RC subunits [5].

Biological context of Muridae

• Functional respiratory chain analyses in murid xenomitochondrial cybrids expose coevolutionary constraints of cytochrome b and nuclear subunits of complex III [5].
• Molecular phylogeny of rodents, with special emphasis on murids: evidence from nuclear gene LCAT [6].
• We carried out a comparative chromosome analysis (R- and C-bands) on two South African murid rodent species, Lemniscomys rosalia and Rhabdomys pumilio, whose banded karyotypes are reported here for the first time [7].
• Synaptonemal complex analysis of B-chromosome behavior in meiotic prophase I in the East-Asiatic mouse Apodemus peninsulae (Muridae, Rodentia) [8].
• Geographical variations in heat production and dissipation within two populations of Rhabdomys pumilio (Muridae) [9].

Anatomical context of Muridae

• Water-deprived cricetids had higher urine osmolalities, urea concentrations and lower daily percentage body water turnovers than the murids [10].
• The fluorescent dye 3, 3' dihexyloxacarbocyanine iodide selectively stains the midpiece and apical region of the heads of murid rodent spermatozoa [11].
• This comparative study of the cDNA sequence of the zona pellucida C (ZPC) glycoprotein in murid rodents focuses on the nucleotide and amino acid sequence of the putative sperm-combining site [12].
• In humans and some murids, the TNF gene is expressed in ovaries, oviducts, uteri, placentas and embryos [13].
• Brain acetylcholinesterase (AChE) and its molecular forms of a precocial murid, Acomys cahirinus, characterized by a large hippocampus, were measured during post-natal development and compared with rat [14].

Associations of Muridae with chemical compounds

• Because the repeat pattern differs in closely related murine taxa, involucrin reveals with greater sensitivity than random nucleotide substitutions the evolutionary relations of the mouse and probably of all murids [15].
• Temporal organization of the 24-h corticosterone rhythm in the diurnal murid rodent Arvicanthis ansorgei Thomas 1910 [16].
• Ultrastructural immunohistochemical localization of vasopressin in the hypothalamic-neurohypophysial system of three murids [17].
• Phylogenetic analysis, including additional murid taxa, showed that the DRB exon 2 sequences did not separate according to species, consistent with trans-species evolution of the MHC in these taxa [18].
• The results suggest that microsomal enzyme activity in the conversion of 7alpha-hydroxycholesterol to 7-ketocholesterol varies considerably, even within the subfamily Cricetinae and the family Muridae [19].

Gene context of Muridae

• Using both simulations and analysis of real data from murids (APRT and LCAT nuclear genes), we show that comparing large numbers of species significantly improves the power of the test [20].
• These results suggest that the expression of the albumin and AFP genes may be subjected to different regulatory events in these two members of the Muridae family [21].
• We explored the phylogenetic potential of indels in four nuclear protein-coding genes (SCA1, PRNP, TNFalpha, and HspB3) with regard to a possible rooting at the murid branch [22].
• All murid LCAT sequences are much poorer in GC than all nonrodent LCAT sequences, and the hamster sequence database shows exactly the same isochore pattern as rat and mouse [23].
• The muridae glyceraldehyde-3-phosphate dehydrogenase family [24].

Analytical, diagnostic and therapeutic context of Muridae

• Northern blot analyses of SubH2Bv mRNA expression showed that it is testis-specific and is also present in murid testes [25].
• In this work, by using immunohistochemistry with five antibodies against calcium-binding proteins (calbindin-D28k, calretinin, calmodulin, neurocalcin and S-100 beta) and Cricetomys gambianus, a rodent belonging to Muridae family living in Africa, we were able to illustrate the presence of neurons in the pineal gland [26].

References