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Gene Review

LHCGR  -  luteinizing hormone/choriogonadotropin...

Gallus gallus

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High impact information on LHCGR


Biological context of LHCGR

  • This study indicated that the marked increase in expression of LHR mRNA in granulosa layer of the F1 follicle might be important for LHR protein synthesis and succeeding bonus progesterone production in F1 follicle destined to ovulation [4].
  • These results suggest that in hen granulosa cells, the mRNA levels of not only LHR but also FSHR are down-regulated by LH and the down-regulation may be mediated steroid hormones [3].

Analytical, diagnostic and therapeutic context of LHCGR


  1. Regulation of steroidogenic acute regulatory protein and luteinizing hormone receptor messenger ribonucleic acid in hen granulosa cells. Johnson, A.L., Bridgham, J.T. Endocrinology (2001) [Pubmed]
  2. Mapping of the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) to chicken chromosome 3. Ge, S.F., Romanov, M.N., Sharp, P.J., Burt, D.W., Paton, I.R., Dunn, I.C. Anim. Genet. (2001) [Pubmed]
  3. Expression of messenger RNA for gonadotropin receptor in the granulosa layer during the ovulatory cycle of hens. Yamamura, N., Takeishi, M., Goto, H., Tagami, M., Mizutani, T., Miyamoto, K., Doi, O., Kamiyoshi, M. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. (2001) [Pubmed]
  4. Expression of messenger ribonucleic acids of luteinizing hormone and follicle-stimulating hormone receptors in granulosa and theca layers of chicken preovulatory follicles. Zhang, C., Shimada, K., Saito, N., Kansaku, N. Gen. Comp. Endocrinol. (1997) [Pubmed]
  5. Molecular cloning and functional expression of chicken luteinizing hormone receptor. Mizutani, T., Minegishi, T., Nonobe, Y., Abe, Y., Hasegawa, Y., Wakabayashi, K., Kamiyoshi, M., Miyamoto, K. Biochim. Biophys. Acta (1998) [Pubmed]
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