Gene Review:
Dcr-1 - Dicer-1
Drosophila melanogaster
Synonyms:
CG4792, DCR-1, DCR1, DICER, Dcr, ...
- A new role for microRNA pathways: modulation of degeneration induced by pathogenic human disease proteins. Bilen, J., Liu, N., Bonini, N.M. Cell Cycle (2006)
- Involvement of microRNA in AU-rich element-mediated mRNA instability. Jing, Q., Huang, S., Guth, S., Zarubin, T., Motoyama, A., Chen, J., Di Padova, F., Lin, S.C., Gram, H., Han, J. Cell (2005)
- Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Lee, Y.S., Nakahara, K., Pham, J.W., Kim, K., He, Z., Sontheimer, E.J., Carthew, R.W. Cell (2004)
- Dicers at RISC; the mechanism of RNAi. Tijsterman, M., Plasterk, R.H. Cell (2004)
- A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Hutvágner, G., McLachlan, J., Pasquinelli, A.E., Bálint, E., Tuschl, T., Zamore, P.D. Science (2001)
- Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Jiang, F., Ye, X., Liu, X., Fincher, L., McKearin, D., Liu, Q. Genes Dev. (2005)
- Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Okamura, K., Ishizuka, A., Siomi, H., Siomi, M.C. Genes Dev. (2004)
- Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. Saito, K., Ishizuka, A., Siomi, H., Siomi, M.C. PLoS Biol. (2005)
- R2D2 leads the silencing trigger to mRNA's death star. Pellino, J.L., Sontheimer, E.J. Cell (2003)
- The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Song, J.J., Liu, J., Tolia, N.H., Schneiderman, J., Smith, S.K., Martienssen, R.A., Hannon, G.J., Joshua-Tor, L. Nat. Struct. Biol. (2003)
- MicroRNAs: Loquacious speaks out. Leuschner, P.J., Obernosterer, G., Martinez, J. Curr. Biol. (2005)
- Dcr-1 maintains Drosophila ovarian stem cells. Jin, Z., Xie, T. Curr. Biol. (2007)
- A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Gunawardane, L.S., Saito, K., Nishida, K.M., Miyoshi, K., Kawamura, Y., Nagami, T., Siomi, H., Siomi, M.C. Science (2007)
- Targets of microRNA regulation in the Drosophila oocyte proteome. Nakahara, K., Kim, K., Sciulli, C., Dowd, S.R., Minden, J.S., Carthew, R.W. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. Förstemann, K., Tomari, Y., Du, T., Vagin, V.V., Denli, A.M., Bratu, D.P., Klattenhoff, C., Theurkauf, W.E., Zamore, P.D. PLoS Biol. (2005)