High impact information on Idh

• Idh is ten map units to the left of Est-6, Odh twelve map units to the right and Ao is seven units beyond Odh [1].
• Adh on the 2nd and Idh, Odh and Ao on the 3rd chromosome showed significant heterozygote deficiencies [1].
• It is suggested that this fairly low level of interpopulation differentiation for the examined loci except Idh may be explained by extensive gene flow in combination with natural selection [2].
• Isocitrate dehydrogenase and phosphoglucomutase were visualized after starch gel electrophoresis of trypanosome lysates [3].
• The Km values for purified NADP-IDH are not different from those found for the purified control enzyme for NADP+ or isocitrate [4].

Associations of Idh with chemical compounds

• Hybrids were identified by the isoenzyme pattern of NADP-dependent isocitrate dehydrogenase [5].
• At two loci, alpha-glycerophosphate dehydrogenase on chromosome 2, and isocitrate dehydrogenase on chromosome 3, allelic variation was detected [6].

Analytical, diagnostic and therapeutic context of Idh

• We also reported a strong maternal effect on these traits, because survivors of a paraquat bioassay carrying cytoplasm inherited from slow developmental long-lived females (S+ cytoplasm) showed the highest frequency of the fast electrophoretical variant of IDH-NADP [7].

References