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HGF  -  hepatocyte growth factor (hepapoietin A;...

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High impact information on HGF


Biological context of HGF

  • In the ovine uterus, HGF may stimulate epithelial morphogenesis and differentiated function required for establishment and maintenance of pregnancy, conceptus implantation, and placentation [3].

Anatomical context of HGF


Other interactions of HGF

  • The RT-PCR analyses indicated that expression of FGF-10, HGF, IGF-I, and IGF-II mRNAs increased in the neonatal uterus between PND 1 and 56 [2].
  • The abundance of mRNA for GH, prolactin, and IGF-II receptors, plus hepatocyte growth factor and suppressor of cytokine signaling-3 were all lower in livers of NR offspring [5].

Analytical, diagnostic and therapeutic context of HGF


  1. Neonatal estrogen exposure disrupts uterine development in the postnatal sheep. Hayashi, K., Carpenter, K.D., Spencer, T.E. Endocrinology (2004) [Pubmed]
  2. Expression of messenger ribonucleic acids for fibroblast growth factors 7 and 10, hepatocyte growth factor, and insulin-like growth factors and their receptors in the neonatal ovine uterus. Taylor, K.M., Chen, C., Gray, C.A., Bazer, F.W., Spencer, T.E. Biol. Reprod. (2001) [Pubmed]
  3. Expression of hepatocyte growth factor and its receptor c-met in the ovine uterus. Chen, C., Spencer, T.E., Bazer, F.W. Biol. Reprod. (2000) [Pubmed]
  4. Pulmonary expression of the hepatocyte growth factor receptor c-Met shifts from medial to intimal layer after cavopulmonary anastomosis. Ikai, A., Riemer, R.K., Ma, X., Reinhartz, O., Hanley, F.L., Reddy, V.M. J. Thorac. Cardiovasc. Surg. (2004) [Pubmed]
  5. Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep. Hyatt, M.A., Gopalakrishnan, G.S., Bispham, J., Gentili, S., McMillen, I.C., Rhind, S.M., Rae, M.T., Kyle, C.E., Brooks, A.N., Jones, C., Budge, H., Walker, D., Stephenson, T., Symonds, M.E. J. Endocrinol. (2007) [Pubmed]
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