Gene Review:
MYO15A - myosin XVA
Homo sapiens
Synonyms:
DFNB3, MYO15, Unconventional myosin-15, Unconventional myosin-XV
- Novel mutations of MYO15A associated with profound deafness in consanguineous families and moderately severe hearing loss in a patient with Smith-Magenis syndrome. Liburd, N., Ghosh, M., Riazuddin, S., Naz, S., Khan, S., Ahmed, Z., Riazuddin, S., Liang, Y., Menon, P.S., Smith, T., Smith, A.C., Chen, K.S., Lupski, J.R., Wilcox, E.R., Potocki, L., Friedman, T.B. Hum. Genet. (2001)
- Myosin XVA expression in the pituitary and in other neuroendocrine tissues and tumors. Lloyd, R.V., Vidal, S., Jin, L., Zhang, S., Kovacs, K., Horvath, E., Scheithauer, B.W., Boger, E.T., Fridell, R.A., Friedman, T.B. Am. J. Pathol. (2001)
- A gene for congenital, recessive deafness DFNB3 maps to the pericentromeric region of chromosome 17. Friedman, T.B., Liang, Y., Weber, J.L., Hinnant, J.T., Barber, T.D., Winata, S., Arhya, I.N., Asher, J.H. Nat. Genet. (1995)
- Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3. Wang, A., Liang, Y., Fridell, R.A., Probst, F.J., Wilcox, E.R., Touchman, J.W., Morton, C.C., Morell, R.J., Noben-Trauth, K., Camper, S.A., Friedman, T.B. Science (1998)
- Unconventional myosins and the genetics of hearing loss. Friedman, T.B., Sellers, J.R., Avraham, K.B. Am. J. Med. Genet. (1999)
- Cloning and chromosomal localization of MYO15A to chromosome 5 of the dog (Canis familiaris). Rak, S.G., Drögemüller, C., Kuiper, H., Leeb, T., Quignon, P., André, C., Distl, O. Chromosome Res. (2002)
- DFNB3, spectrum of MYO15A recessive mutant alleles and an emerging genotype-phenotype correlation. Friedman, T.B., Hinnant, J.T., Ghosh, M., Boger, E.T., Riazuddin, S., Lupski, J.R., Potocki, L., Wilcox, E.R. Adv. Otorhinolaryngol. (2002)
- Auditory mechanotransduction in the absence of functional myosin-XVa. Stepanyan, R., Belyantseva, I.A., Griffith, A.J., Friedman, T.B., Frolenkov, G.I. J. Physiol. (Lond.) (2006)
- Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2. Liang, Y., Wang, A., Belyantseva, I.A., Anderson, D.W., Probst, F.J., Barber, T.D., Miller, W., Touchman, J.W., Jin, L., Sullivan, S.L., Sellers, J.R., Camper, S.A., Lloyd, R.V., Kachar, B., Friedman, T.B., Fridell, R.A. Genomics (1999)
- Human myosin XVBP is a transcribed pseudogene. Boger, E.T., Sellers, J.R., Friedman, T.B. J. Muscle Res. Cell. Motil. (2001)
- The roles of unconventional myosins in hearing and deafness. Libby, R.T., Steel, K.P. Essays Biochem. (2000)
- A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expression. Schneider, M.E., Dos??, A.C., Salles, F.T., Chang, W., Erickson, F.L., Burnside, B., Kachar, B. J. Neurosci. (2006)