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Gene Review

CLDN18  -  claudin 18

Homo sapiens

Synonyms: Claudin-18, SFTA5, SFTPJ, UNQ778/PRO1572
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Disease relevance of CLDN18


High impact information on CLDN18


Biological context of CLDN18


Anatomical context of CLDN18


Analytical, diagnostic and therapeutic context of CLDN18


  1. The claudin gene family: expression in normal and neoplastic tissues. Hewitt, K.J., Agarwal, R., Morin, P.J. BMC Cancer (2006) [Pubmed]
  2. Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype. Sanada, Y., Oue, N., Mitani, Y., Yoshida, K., Nakayama, H., Yasui, W. J. Pathol. (2006) [Pubmed]
  3. claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. Niimi, T., Nagashima, K., Ward, J.M., Minoo, P., Zimonjic, D.B., Popescu, N.C., Kimura, S. Mol. Cell. Biol. (2001) [Pubmed]
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