Gene Review:
PFKFB4 - 6-phosphofructo-2-kinase/fructose-2,6...
Homo sapiens
Synonyms:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, 6PF-2-K/Fru-2,6-P2ase 4, 6PF-2-K/Fru-2,6-P2ase testis-type isozyme, PFK/FBPase 4
Minchenko,
Ogura,
Opentanova,
Minchenko,
Esumi,
Minchenko,
Opentanova,
Minchenko,
Ogura,
Esumi,
Minchenko,
Opentanova,
Ogura,
Minchenko,
Komisarenko,
Caro,
Esumi,
- Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation. Minchenko, O., Opentanova, I., Minchenko, D., Ogura, T., Esumi, H. FEBS Lett. (2004)
- Expression and hypoxia-responsiveness of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 in mammary gland malignant cell lines. Minchenko, O.H., Opentanova, I.L., Ogura, T., Minchenko, D.O., Komisarenko, S.V., Caro, J., Esumi, H. Acta Biochim. Pol. (2005)
- Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: expression and hypoxic regulation. Minchenko, O.H., Ogura, T., Opentanova, I.L., Minchenko, D.O., Esumi, H. Mol. Cell. Biochem. (2005)
- Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers. Bobarykina, A.Y., Minchenko, D.O., Opentanova, I.L., Moenner, M., Caro, J., Esumi, H., Minchenko, O.H. Acta Biochim. Pol. (2006)
- Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy. Kim, S.G., Manes, N.P., El-Maghrabi, M.R., Lee, Y.H. J. Biol. Chem. (2006)
- Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region. Gómez, M., Manzano, A., Navarro-Sabaté, A., Duran, J., Obach, M., Perales, J.C., Bartrons, R. FEBS Lett. (2005)