Gene Review:
YPT6 - Rab family GTPase YPT6
Saccharomyces cerevisiae S288c
Synonyms:
GTP-binding protein YPT6, L8479.11, YLR262C
- A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family. Strom, M., Vollmer, P., Tan, T.J., Gallwitz, D. Nature (1993)
- An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export. Votsmeier, C., Gallwitz, D. EMBO J. (2001)
- Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. Siniossoglou, S., Peak-Chew, S.Y., Pelham, H.R. EMBO J. (2000)
- The GTPase-activating enzyme Gyp1p is required for recycling of internalized membrane material by inactivation of the Rab/Ypt GTPase Ypt1p. Lafourcade, C., Galan, J.M., Gloor, Y., Haguenauer-Tsapis, R., Peter, M. Mol. Cell. Biol. (2004)
- Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartments. Luo, Z., Gallwitz, D. J. Biol. Chem. (2003)
- Isolation and characterization of SYS genes from yeast, multicopy suppressors of the functional loss of the transport GTPase Ypt6p. Tsukada, M., Gallwitz, D. J. Cell. Sci. (1996)
- Structural and functional analysis of a novel coiled-coil protein involved in Ypt6 GTPase-regulated protein transport in yeast. Tsukada, M., Will, E., Gallwitz, D. Mol. Biol. Cell (1999)
- A small GTP-binding protein from Arabidopsis thaliana functionally complements the yeast YPT6 null mutant. Bednarek, S.Y., Reynolds, T.L., Schroeder, M., Grabowski, R., Hengst, L., Gallwitz, D., Raikhel, N.V. Plant Physiol. (1994)
- Characterization of membrane-bound small GTP-binding proteins from Nicotiana tabacum. Haizel, T., Merkle, T., Turck, F., Nagy, F. Plant Physiol. (1995)
- Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesis. Li, B., Warner, J.R. J. Biol. Chem. (1996)
- Affinity purification of Ypt6 effectors and identification of TMF/ARA160 as a Rab6 interactor. Siniossoglou, S. Meth. Enzymol. (2005)
- Genetic interaction between YPT6 and YPT1 in Saccharomyces cerevisiae. Li, B., Warner, J.R. Yeast (1998)
- Ric1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane proteins. Bensen, E.S., Yeung, B.G., Payne, G.S. Mol. Biol. Cell (2001)