Gene Review:
CDC53 - cullin CDC53
Saccharomyces cerevisiae S288c
Synonyms:
Cell division control protein 53, Cullin-A, D2190, E3 ubiquitin ligase complex SCF subunit CDC53, YDL132W
- Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway. Willems, A.R., Lanker, S., Patton, E.E., Craig, K.L., Nason, T.F., Mathias, N., Kobayashi, R., Wittenberg, C., Tyers, M. Cell (1996)
- Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Seol, J.H., Feldman, R.M., Zachariae, W., Shevchenko, A., Correll, C.C., Lyapina, S., Chi, Y., Galova, M., Claypool, J., Sandmeyer, S., Nasmyth, K., Deshaies, R.J., Shevchenko, A., Deshaies, R.J. Genes Dev. (1999)
- Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Lammer, D., Mathias, N., Laplaza, J.M., Jiang, W., Liu, Y., Callis, J., Goebl, M., Estelle, M. Genes Dev. (1998)
- Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Patton, E.E., Willems, A.R., Sa, D., Kuras, L., Thomas, D., Craig, K.L., Tyers, M. Genes Dev. (1998)
- Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins. Mathias, N., Johnson, S.L., Winey, M., Adams, A.E., Goetsch, L., Pringle, J.R., Byers, B., Goebl, M.G. Mol. Cell. Biol. (1996)
- The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast. Kondo-Okamoto, N., Ohkuni, K., Kitagawa, K., McCaffery, J.M., Shaw, J.M., Okamoto, K. Mol. Biol. Cell (2006)
- Palindrome content of the yeast Saccharomyces cerevisiae genome. Lisnić, B., Svetec, I.K., Sarić, H., Nikolić, I., Zgaga, Z. Curr. Genet. (2005)
- Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae. Arnason, T.G., Pisclevich, M.G., Dash, M.D., Davies, G.F., Harkness, T.A. Eukaryotic Cell (2005)
- The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Kurz, T., Ozlü, N., Rudolf, F., O'Rourke, S.M., Luke, B., Hofmann, K., Hyman, A.A., Bowerman, B., Peter, M. Nature (2005)
- An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiae. Mathias, N., Steussy, C.N., Goebl, M.G. J. Biol. Chem. (1998)
- SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis. Willems, A.R., Goh, T., Taylor, L., Chernushevich, I., Shevchenko, A., Tyers, M. Philos. Trans. R. Soc. Lond., B, Biol. Sci. (1999)
- Sgt1p contributes to cyclic AMP pathway activity and physically interacts with the adenylyl cyclase Cyr1p/Cdc35p in budding yeast. Dubacq, C., Guerois, R., Courbeyrette, R., Kitagawa, K., Mann, C. Eukaryotic Cell (2002)
- Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Seol, J.H., Shevchenko, A., Shevchenko, A., Deshaies, R.J. Nat. Cell Biol. (2001)
- Cell cycle: cull and destroy. Jackson, P.K. Curr. Biol. (1996)