Gene Review:
CDC4 - SCF ubiquitin ligase complex subunit CDC4
Saccharomyces cerevisiae S288c
Synonyms:
Cell division control protein 4, E3 ubiquitin ligase complex SCF subunit CDC4, F-box protein CDC4, YFL009W
- A relationship between the yeast cell cycle genes CDC4 and CDC36 and the ets sequence of oncogenic virus E26. Peterson, T.A., Yochem, J., Byers, B., Nunn, M.F., Duesberg, P.H., Doolittle, R.F., Reed, S.I. Nature (1984)
- Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Chou, S., Huang, L., Liu, H. Cell (2004)
- A deduced gene product from the Drosophila neurogenic locus, enhancer of split, shows homology to mammalian G-protein beta subunit. Hartley, D.A., Preiss, A., Artavanis-Tsakonas, S. Cell (1988)
- Genes that act before conjugation to prepare the Saccharomyces cerevisiae nucleus for caryogamy. Dutcher, S.K., Hartwell, L.H. Cell (1983)
- Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nash, P., Tang, X., Orlicky, S., Chen, Q., Gertler, F.B., Mendenhall, M.D., Sicheri, F., Pawson, T., Tyers, M. Nature (2001)
- Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae. Goh, P.Y., Surana, U. Mol. Cell. Biol. (1999)
- G2/M checkpoint genes of Saccharomyces cerevisiae: further evidence for roles in DNA replication and/or repair. Lydall, D., Weinert, T. Mol. Gen. Genet. (1997)
- The CDC4 gene product is associated with the yeast nuclear skeleton. Choi, W.J., Clark, M.W., Chen, J.X., Jong, A.Y. Biochem. Biophys. Res. Commun. (1990)
- sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast. Jallepalli, P.V., Tien, D., Kelly, T.J. Proc. Natl. Acad. Sci. U.S.A. (1998)
- DNA ethylations induced by ethylnitrosourea in the wild type, cdc4 and cdc7 strains of Saccharomyces cerevisiae. Fox, J.C., Edwards, S., Waters, R. Mutagenesis (1986)
- An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiae. Mathias, N., Steussy, C.N., Goebl, M.G. J. Biol. Chem. (1998)
- Cic1, an adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component Cdc4. Jäger, S., Strayle, J., Heinemeyer, W., Wolf, D.H. EMBO J. (2001)
- SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities. Verma, R., Feldman, R.M., Deshaies, R.J. Mol. Biol. Cell (1997)
- The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae. Sánchez, M., Calzada, A., Bueno, A. J. Biol. Chem. (1999)
- SCM4, a gene that suppresses mutant cdc4 function in budding yeast. Smith, S.A., Kumar, P., Johnston, I., Rosamond, J. Mol. Gen. Genet. (1992)
- The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1. Knapp, D., Bhoite, L., Stillman, D.J., Nasmyth, K. Mol. Cell. Biol. (1996)
- Starting to cycle: G1 controls regulating cell division in budding yeast. Sherlock, G., Rosamond, J. J. Gen. Microbiol. (1993)