Gene Review:
TAP42 - Tap42p
Saccharomyces cerevisiae S288c
Synonyms:
Type 2A phosphatase-associated protein 42, YM9711.18, YM9973.01C, YMR028W
- The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Beck, T., Hall, M.N. Nature (1999)
- Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2. Cherkasova, V.A., Hinnebusch, A.G. Genes Dev. (2003)
- Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases. Di Como, C.J., Arndt, K.T. Genes Dev. (1996)
- Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast. Düvel, K., Santhanam, A., Garrett, S., Schneper, L., Broach, J.R. Mol. Cell (2003)
- Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway. Onda, M., Inui, S., Maeda, K., Suzuki, M., Takahashi, E., Sakaguchi, N. Genomics (1997)
- Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast. Jiang, Y., Broach, J.R. EMBO J. (1999)
- LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast. Araki, T., Uesono, Y., Oguchi, T., Toh-E, A. Genes Genet. Syst. (2005)
- PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p. Santhanam, A., Hartley, A., Düvel, K., Broach, J.R., Garrett, S. Eukaryotic Cell (2004)
- TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Jacinto, E., Guo, B., Arndt, K.T., Schmelzle, T., Hall, M.N. Mol. Cell (2001)
- Saccharomyces cerevisiae Sit4 Phosphatase Is Active Irrespective of the Nitrogen Source Provided, and Gln3 Phosphorylation Levels Become Nitrogen Source-responsive in a sit4-deleted Strain. Tate, J.J., Feller, A., Dubois, E., Cooper, T.G. J. Biol. Chem. (2006)
- The Tap42-protein phosphatase type 2A catalytic subunit complex is required for cell cycle-dependent distribution of actin in yeast. Wang, H., Jiang, Y. Mol. Cell. Biol. (2003)
- The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. Schmidt, A., Beck, T., Koller, A., Kunz, J., Hall, M.N. EMBO J. (1998)
- Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Schmelzle, T., Beck, T., Martin, D.E., Hall, M.N. Mol. Cell. Biol. (2004)
- Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots. Cooper, T.G. FEMS Microbiol. Rev. (2002)
- Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2. Van Hoof, C., Martens, E., Longin, S., Jordens, J., Stevens, I., Janssens, V., Goris, J. Biochem. J. (2005)