Gene Review:
IGBP1 - immunoglobulin (CD79A) binding protein 1
Homo sapiens
Synonyms:
ALPHA-4, B-cell signal transduction molecule alpha 4, CD79a-binding protein 1, IBP1, Immunoglobulin-binding protein 1, ...
- A new X-linked syndrome with agenesis of the corpus callosum, mental retardation, coloboma, micrognathia, and a mutation in the Alpha 4 gene at Xq13. Graham, J.M., Wheeler, P., Tackels-Horne, D., Lin, A.E., Hall, B.D., May, M., Short, K.M., Schwartz, C.E., Cox, T.C. Am. J. Med. Genet. A (2003)
- The alpha promoter regulator-ovalbumin chimeric gene resident in human cells is regulated like the authentic alpha 4 gene after infection with herpes simplex virus 1 mutants in alpha 4 gene. Herz, C., Roizman, B. Cell (1983)
- Aerobic anoxygenic phototrophic bacteria. Yurkov, V.V., Beatty, J.T. Microbiol. Mol. Biol. Rev. (1998)
- The alpha 5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain. Conroy, W.G., Vernallis, A.B., Berg, D.K. Neuron (1992)
- Upregulated expression and function of integrin adhesive receptors in systemic lupus erythematosus patients with vasculitis. Takeuchi, T., Amano, K., Sekine, H., Koide, J., Abe, T. J. Clin. Invest. (1993)
- Mutational analysis of the nicotinic acetylcholine receptor alpha 4 subunit gene in attention deficit/hyperactivity disorder: evidence for association of an intronic polymorphism with attention problems. Todd, R.D., Lobos, E.A., Sun, L.W., Neuman, R.J. Mol. Psychiatry (2003)
- Nicotinic receptor subtypes and cognitive function. Levin, E.D. J. Neurobiol. (2002)
- Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains. Warpman, U., Nordberg, A. Neuroreport (1995)
- Appearance of localized immunoreactivity for the alpha 4 integrin subunit and for fibronectin in brains from Alzheimer's, Lewy body dementia patients and aged controls. Van Gool, D., Carmeliet, G., Triau, E., Cassiman, J.J., Dom, R. Neurosci. Lett. (1994)
- Neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) and panic disorder: an association study. Steinlein, O.K., Deckert, J., Nöthen, M.M., Franke, P., Maier, W., Beckmann, H., Propping, P. Am. J. Med. Genet. (1997)
- A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy. Steinlein, O.K., Mulley, J.C., Propping, P., Wallace, R.H., Phillips, H.A., Sutherland, G.R., Scheffer, I.E., Berkovic, S.F. Nat. Genet. (1995)
- L-selectin-mediated lymphocyte rolling on MAdCAM-1. Berg, E.L., McEvoy, L.M., Berlin, C., Bargatze, R.F., Butcher, E.C. Nature (1993)
- Metal ion-dependent modulation of the dynamics of a designed protein. Handel, T.M., Williams, S.A., DeGrado, W.F. Science (1993)
- Leukocyte integrins. Stewart, M., Thiel, M., Hogg, N. Curr. Opin. Cell Biol. (1995)
- Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin alpha 4 beta 7. Hesterberg, P.E., Winsor-Hines, D., Briskin, M.J., Soler-Ferran, D., Merrill, C., Mackay, C.R., Newman, W., Ringler, D.J. Gastroenterology (1996)
- Coordinate role for cell surface chondroitin sulfate proteoglycan and alpha 4 beta 1 integrin in mediating melanoma cell adhesion to fibronectin. Iida, J., Skubitz, A.P., Furcht, L.T., Wayner, E.A., McCarthy, J.B. J. Cell Biol. (1992)
- Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis. Benetti, L., Roizman, B. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Thiol/disulfide formation associated with the redox activity of the [Fe3S4] cluster of Desulfovibrio gigas ferredoxin II. 1H NMR and Mössbauer spectroscopic study. Macedo, A.L., Moura, I., Surerus, K.K., Papaefthymiou, V., Liu, M.Y., LeGall, J., Münck, E., Moura, J.J. J. Biol. Chem. (1994)
- The novel recognition site in the C-terminal heparin-binding domain of fibronectin by integrin alpha 4 beta 1 receptor on HL-60 cells. Mohri, H., Katoh, K., Iwamatsu, A., Okubo, T. Exp. Cell Res. (1996)
- MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. Short, K.M., Hopwood, B., Yi, Z., Cox, T.C. BMC Cell Biol. (2002)
- Solution structure of the RBCC/TRIM B-box1 domain of human MID1: B-box with a RING. Massiah, M.A., Simmons, B.N., Short, K.M., Cox, T.C. J. Mol. Biol. (2006)
- Contiguous localization of the genes encoding human insulin-like growth factor binding proteins 1 (IGBP1) and 3 (IGBP3) on chromosome 7. Ehrenborg, E., Larsson, C., Stern, I., Janson, M., Powell, D.R., Luthman, H. Genomics (1992)
- Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4. Liu, J., Prickett, T.D., Elliott, E., Meroni, G., Brautigan, D.L. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway. Onda, M., Inui, S., Maeda, K., Suzuki, M., Takahashi, E., Sakaguchi, N. Genomics (1997)
- Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin. Kassner, P.D., Hemler, M.E. J. Exp. Med. (1993)
- Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the alternatively spliced domain of vascular cell adhesion molecule 1 and an additional alpha 4 integrin counter-receptor on stimulated endothelium. Vonderheide, R.H., Springer, T.A. J. Exp. Med. (1992)
- Dual binding capacity of mucosal immunoblasts to mucosal and synovial endothelium in humans: dissection of the molecular mechanisms. Salmi, M., Andrew, D.P., Butcher, E.C., Jalkanen, S. J. Exp. Med. (1995)
- Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits. Prickett, T.D., Brautigan, D.L. J. Biol. Chem. (2004)
- Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein. Nojima, Y., Rothstein, D.M., Sugita, K., Schlossman, S.F., Morimoto, C. J. Exp. Med. (1992)
- The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function. Takada, Y., Elices, M.J., Crouse, C., Hemler, M.E. EMBO J. (1989)
- Critical amino acid residues for ligand binding are clustered in a predicted beta-turn of the third N-terminal repeat in the integrin alpha 4 and alpha 5 subunits. Irie, A., Kamata, T., Puzon-McLaughlin, W., Takada, Y. EMBO J. (1995)
- Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. Wayner, E.A., Garcia-Pardo, A., Humphries, M.J., McDonald, J.A., Carter, W.G. J. Cell Biol. (1989)
- Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY. Chan, B.M., Elices, M.J., Murphy, E., Hemler, M.E. J. Biol. Chem. (1992)
- Adhesion of osteosarcoma cells to the 70-kDa core region of thrombospondin-1 is mediated by the alpha 4 beta 1 integrin. Decker, S., van Valen, F., Vischer, P. Biochem. Biophys. Res. Commun. (2002)
- Post-translational processing of the leukocyte integrin alpha 4 beta 1. Bednarczyk, J.L., Szabo, M.C., McIntyre, B.W. J. Biol. Chem. (1992)
- VCAM-1 is internalized by a clathrin-related pathway in human endothelial cells but its alpha 4 beta 1 integrin counter-receptor remains associated with the plasma membrane in human T lymphocytes. Ricard, I., Payet, M.D., Dupuis, G. Eur. J. Immunol. (1998)
- A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration. Liu, S., Kiosses, W.B., Rose, D.M., Slepak, M., Salgia, R., Griffin, J.D., Turner, C.E., Schwartz, M.A., Ginsberg, M.H. J. Biol. Chem. (2002)
- Focal adhesion kinase (pp125FAK) is tyrosine phosphorylated after engagement of alpha 4 beta 1 and alpha 5 beta 1 integrins on human T-lymphoblastic cells. Nojima, Y., Tachibana, K., Sato, T., Schlossman, S.F., Morimoto, C. Cell. Immunol. (1995)
- Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29). Mannion, B.A., Berditchevski, F., Kraeft, S.K., Chen, L.B., Hemler, M.E. J. Immunol. (1996)
- Co-clustering of beta 1 integrins, cytoskeletal proteins, and tyrosine-phosphorylated substrates during integrin-mediated leukocyte aggregation. Sánchez-Mateos, P., Campanero, M.R., Balboa, M.A., Sánchez-Madrid, F. J. Immunol. (1993)
- Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2. Chung, H., Nairn, A.C., Murata, K., Brautigan, D.L. Biochemistry (1999)
- Counter-receptors on human basophils for endothelial cell adhesion molecules. Bochner, B.S., Sterbinsky, S.A., Briskin, M., Saini, S.S., MacGlashan, D.W. J. Immunol. (1996)
- Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. Jiang, Y., Beller, D.I., Frendl, G., Graves, D.T. J. Immunol. (1992)
- VLA-4 integrin can mediate CD11/CD18-independent transendothelial migration of human monocytes. Chuluyan, H.E., Issekutz, A.C. J. Clin. Invest. (1993)
- Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function. Bhatia, R., Wayner, E.A., McGlave, P.B., Verfaillie, C.M. J. Clin. Invest. (1994)
- A monoclonal antibody to beta 1 integrin (CD29) stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components. Kovach, N.L., Carlos, T.M., Yee, E., Harlan, J.M. J. Cell Biol. (1992)
- IFN-gamma and transforming growth factor-beta 1 differently regulate fibronectin and laminin receptors of human differentiating monocytic cells. Bauvois, B., Rouillard, D., Sanceau, J., Wietzerbin, J. J. Immunol. (1992)
- Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. Miyake, K., Weissman, I.L., Greenberger, J.S., Kincade, P.W. J. Exp. Med. (1991)
- Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the compartmentalization of effector B cell responses. Quiding-Järbrink, M., Nordström, I., Granström, G., Kilander, A., Jertborn, M., Butcher, E.C., Lazarovits, A.I., Holmgren, J., Czerkinsky, C. J. Clin. Invest. (1997)
- Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering. Rüegg, C., Postigo, A.A., Sikorski, E.E., Butcher, E.C., Pytela, R., Erle, D.J. J. Cell Biol. (1992)