The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

LRRC4B  -  leucine rich repeat containing 4B

Homo sapiens

Synonyms: DKFZp761A179, HSM, LRIG4, Leucine-rich repeat-containing protein 4B, NGL-3, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of LRRC4B

 

High impact information on LRRC4B

 

Biological context of LRRC4B

  • We studied the effect of media composition on sperm capacitation, using Biggers-Whitten-Whittingham (BWW) medium, Ham's-F10 and a modified Tyrode's medium (HSM) supplemented with bovine serum albumin (BSA) or fetal cord serum (FCS) [6].
  • In addition, these subjects presented the highest diastolic and systolic pressure peaks (HSM 37/42 versus HPM 35/36 and HC 29/31) also during the night (nocturnal peak: HSM 15/19 versus HPM 10/12 and HC 5/15) [7].
 

Associations of LRRC4B with chemical compounds

  • Yet short-term clinical evaluation revealed significantly less reaction in eyes with the HSM IOL than in those with the PMMA lens [5].
  • For the latter only the HSM (heparin surface modifying) technique is currently used [8].
 

Analytical, diagnostic and therapeutic context of LRRC4B

  • Nineteen patients in Group 1 had bilateral cataract extraction with implantation of an HSM IOL in one eye and a conventional lens in the fellow eye [5].
  • Clinical and histopathological studies indicate that heparin-surface-modified intraocular lenses (HSM IOLs) can reduce postoperative anterior segment inflammation [1].
  • We synthesized the corresponding antisense peptides HTCAh, HSM-alpha and HSM-beta and analyzed them for specific interaction with the sense peptides using several types of binding assay and bioassay [9].

References

  1. Heparin-surface-modified intraocular lens implantation in eyes with pseudoexfoliation syndrome. Ravalico, G., Tognetto, D., Baccara, F. Journal of cataract and refractive surgery. (1994) [Pubmed]
  2. Isolation and characterization of a partial cDNA for a human sialyltransferase. Lance, P., Lau, K.M., Lau, J.T. Biochem. Biophys. Res. Commun. (1989) [Pubmed]
  3. Development of low- and high-serum culture conditions for use of human oral fibroblasts in toxicity testing of dental materials. Liu, Y., Arvidson, K., Atzori, L., Sundqvist, K., Silva, B., Cotgreave, I., Grafström, R.C. J. Dent. Res. (1991) [Pubmed]
  4. Adhesion mechanisms of human lens epithelial cells on 4 intraocular lens materials. Versura, P., Torreggiani, A., Cellini, M., Caramazza, R. Journal of cataract and refractive surgery. (1999) [Pubmed]
  5. Heparin-surface-modified intraocular lens implantation in patients with glaucoma, diabetes, or uveitis. Lin, C.L., Wang, A.G., Chou, J.C., Shieh, G., Liu, J.H. Journal of cataract and refractive surgery. (1994) [Pubmed]
  6. Chemical composition and protein source in the capacitation medium significantly affect the ability of human spermatozoa to undergo follicular fluid induced acrosome reaction. Calvo, L., Dennison-Lagos, L., Banks, S.M., Fugger, E.F., Sherins, R.J. Hum. Reprod. (1993) [Pubmed]
  7. Blood pressure variations assessed by continuous 24-hour monitoring in menopausal and climacteric women. Noto, R., Rapisarda, A., Mirabella, C., Landolina, C., Meli, S., Leanza, A., Quartarone, D., Rizzo, S., Sciacchitano, G. European review for medical and pharmacological sciences. (2000) [Pubmed]
  8. Biocompatibility and IOL. Janssen, S. Bulletin de la Société belge d'ophtalmologie. (1992) [Pubmed]
  9. Antisense peptides: tools for receptor isolation? Lack of antisense MSH and ACTH to interact with their sense peptides and to induce receptor-specific antibodies. Eberle, A.N., Huber, M. J. Recept. Res. (1991) [Pubmed]
 
WikiGenes - Universities