Disease relevance of Birth Injuries

• Other factors were: head injury, birth injury, CNS infections, cerebrovascular accidents, intracranial space occupying lesions and sickle cell disease; 39% of patients with partial epilepsy had acquired aetiological factors [1].
• Fever of unknown cause, asphyxia, birth injury, infection of the central nervous system, tuberous sclerosis, phenylketonuria and recent immunization etc. were complained [2].
• The possible role of cerebral birth injury in the aetiology of epilepsy was evaluated by comparing the birth histories of 101 epileptic patients with focal seizures and 208 with non-focal seizures [3].
• Childhood febrile convulsion was commonly associated with partial epilepsy with complex symptoms while birth injury and CNS infections were associated with generalised epilepsy [4].

High impact information on Birth Injuries

• These pathological features are distinct from other combined degenerations of liver and brain and the cortical lesions differ significantly from the neuropathological sequelae of birth injury or severe epilepsy [5].
• Between group statistically significant (at least P < 0.05) results showed: (1) In Birth injury, 33% had Ammon's Horn (AH) neuron loss under 50%, 54% had other temporal neocortical pathologies, they showed the most CA4 neuron loss, and the worse seizure outcomes [6].
• TLE patients (n = 120) from a single epilepsy center were retrospectively and blindly catalogued into pathogenic groups (independent variables) based on if there was a significant Birth injury (n = 11) or Cerebral trauma (n = 26) [6].
• The fourth patient had rheumatoid arthritis, and the fifth had sustained a birth injury to the brachial plexus [7].
• From these simple measurements, several dozen disease states are recognized, including birth injury, and white matter and Alzheimer disease [8].

Gene context of Birth Injuries

• In more than 80% of patients the presence or absence of birth injury, febrile convulsions in childhood, and a family history of epilepsy were not mentioned [9].
• CONCLUSIONS: Brain lesions that may disturb normal maturation of the visuomotor system and eventually lead to strabismus could be found in some patients without any episode that would cause birth injury [10].
• [N Engl J Med 1999;341:1709-1714], and suggest that the method of assisted delivery, rather than the urgency of the delivery or dysfunctional labor per se, is a more important variable in cranial birth injuries [11].
• Legal case briefs for nurses. ME: OBS: birth injury; paralysis. GA: "Good Samaritan" nurse injured [12].
• OBJECTIVE: To assess the incidence of birth-injuries seen at the King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia (KSA) [13].

References