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MeSH Review

Colorectal Neoplasms, Hereditary Nonpolyposis

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Disease relevance of Colorectal Neoplasms, Hereditary Nonpolyposis


High impact information on Colorectal Neoplasms, Hereditary Nonpolyposis


Chemical compound and disease context of Colorectal Neoplasms, Hereditary Nonpolyposis


Biological context of Colorectal Neoplasms, Hereditary Nonpolyposis


Anatomical context of Colorectal Neoplasms, Hereditary Nonpolyposis


Gene context of Colorectal Neoplasms, Hereditary Nonpolyposis


Analytical, diagnostic and therapeutic context of Colorectal Neoplasms, Hereditary Nonpolyposis


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  4. Women with synchronous primary cancers of the endometrium and ovary: do they have Lynch syndrome? Soliman, P.T., Broaddus, R.R., Schmeler, K.M., Daniels, M.S., Gonzalez, D., Slomovitz, B.M., Gershenson, D.M., Lu, K.H. J. Clin. Oncol. (2005) [Pubmed]
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  6. A role for MLH3 in hereditary nonpolyposis colorectal cancer. Wu, Y., Berends, M.J., Sijmons, R.H., Mensink, R.G., Verlind, E., Kooi, K.A., van der Sluis, T., Kempinga, C., van dDer Zee, A.G., Hollema, H., Buys, C.H., Kleibeuker, J.H., Hofstra, R.M. Nat. Genet. (2001) [Pubmed]
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  9. Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms. Wu, Y., Berends, M.J., Post, J.G., Mensink, R.G., Verlind, E., Van Der Sluis, T., Kempinga, C., Sijmons, R.H., van der Zee, A.G., Hollema, H., Kleibeuker, J.H., Buys, C.H., Hofstra, R.M. Gastroenterology (2001) [Pubmed]
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  14. Novel hMLH1 and hMSH2 germline mutations in African Americans with colorectal cancer. Weber, T.K., Chin, H.M., Rodriguez-Bigas, M., Keitz, B., Gilligan, R., O'Malley, L., Urf, E., Diba, N., Pazik, J., Petrelli, N.J. JAMA (1999) [Pubmed]
  15. Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage. Nyström-Lahti, M., Parsons, R., Sistonen, P., Pylkkänen, L., Aaltonen, L.A., Leach, F.S., Hamilton, S.R., Watson, P., Bronson, E., Fusaro, R. Am. J. Hum. Genet. (1994) [Pubmed]
  16. Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families. Tannergård, P., Lipford, J.R., Kolodner, R., Frödin, J.E., Nordenskjöld, M., Lindblom, A. Cancer Res. (1995) [Pubmed]
  17. Genetic heterogeneity and unmapped genes for colorectal cancer. Lewis, C.M., Neuhausen, S.L., Daley, D., Black, F.J., Swensen, J., Burt, R.W., Cannon-Albright, L.A., Skolnick, M.H. Cancer Res. (1996) [Pubmed]
  18. Nuclear localization of Dpc4 (Madh4, Smad4) in colorectal carcinomas and relation to mismatch repair/transforming growth factor-beta receptor defects. Montgomery, E., Goggins, M., Zhou, S., Argani, P., Wilentz, R., Kaushal, M., Booker, S., Romans, K., Bhargava, P., Hruban, R., Kern, S. Am. J. Pathol. (2001) [Pubmed]
  19. Different mechanisms underlie DNA instability in Huntington disease and colorectal cancer. Goellner, G.M., Tester, D., Thibodeau, S., Almqvist, E., Goldberg, Y.P., Hayden, M.R., McMurray, C.T. Am. J. Hum. Genet. (1997) [Pubmed]
  20. Microsatellite instability and expression of MLH1 and MSH2 in carcinomas of the small intestine. Planck, M., Ericson, K., Piotrowska, Z., Halvarsson, B., Rambech, E., Nilbert, M. Cancer (2003) [Pubmed]
  21. Familial mutations in PMS2 can cause autosomal dominant hereditary nonpolyposis colorectal cancer. Worthley, D.L., Walsh, M.D., Barker, M., Ruszkiewicz, A., Bennett, G., Phillips, K., Suthers, G. Gastroenterology (2005) [Pubmed]
  22. Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant. Berends, M.J., Wu, Y., Sijmons, R.H., Mensink, R.G., van der Sluis, T., Hordijk-Hos, J.M., de Vries, E.G., Hollema, H., Karrenbeld, A., Buys, C.H., van der Zee, A.G., Hofstra, R.M., Kleibeuker, J.H. Am. J. Hum. Genet. (2002) [Pubmed]
  23. Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome. Sun, X., Zheng, L., Shen, B. Cancer Res. (2002) [Pubmed]
  24. BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Deng, G., Bell, I., Crawley, S., Gum, J., Terdiman, J.P., Allen, B.A., Truta, B., Sleisenger, M.H., Kim, Y.S. Clin. Cancer Res. (2004) [Pubmed]
  25. Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer. de Jong, A.E., van Puijenbroek, M., Hendriks, Y., Tops, C., Wijnen, J., Ausems, M.G., Meijers-Heijboer, H., Wagner, A., van Os, T.A., Bröcker-Vriends, A.H., Vasen, H.F., Morreau, H. Clin. Cancer Res. (2004) [Pubmed]
  26. Genetic screening for colorectal cancer and intervention. Alberts, D.S., Lipkin, M., Levin, B. Int. J. Cancer (1996) [Pubmed]
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