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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Baritop     barium(+2) cation sulfate

Synonyms: Bakontal, Baroloid, Barytgen, Baryxine, Bayrites, ...
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Disease relevance of Baritop

  • 'Radiopaque' foreign bodies [1].
  • Diaphragmatic and retrosternal lymph vessels became radiopaque within 30 hours of the ip injection of radiopaque contrast material in control animals without ascites and in 12 experimental mice receiving contrast material 1-3 days after injection of tumor cells [2].
  • Using the radionuclide technique, postprandial gallbladder emptying (t1/2) was prolonged (p less than 0.01) both in patients with radiopaque (26.7 +/- 3.1 min, mean +/- SEM) and radiolucent (21.7 +/- 3.1) gallstones when compared with controls (10.2 +/- 1.5) [3].
  • The purposes of this study were to determine the association, in 10 pedigrees, between adenomatous polyposis coli, hereditary nonpolyposis colorectal cancer, and occult radiopaque jaw lesions, and to assess whether these radiodensities are predictors for adenomatous polyposis [4].
  • In contrast, not all of the solid radiopaque markers emptied from the stomach by 6 h in 16 of 26 experiments in patients with diabetes mellitus (p less than 0.001 vs. healthy controls) [5].

Psychiatry related information on Baritop

  • Transit time studies were performed using 10 radiopaque markers [6].
  • Group 1 (n = 25) ingested 150-mL aliquots of 2% barium sulfate suspension with meals and snacks for 48 hours prior to imaging, without other diet modification or a cathartic [7].
  • In patients with a history of radiopaque stones in this size range, therefore, AXR may provide useful size data for clinical decision-making without concern about significant disparities between the two modalities [8].

High impact information on Baritop


Chemical compound and disease context of Baritop


Biological context of Baritop

  • Influence of food and marker length on gastric emptying of indigestible radiopaque markers in healthy humans [18].
  • The distances between three or four radiopaque markers located on the left ventricular epicardial surface at the apex and in the region of the minor axes in 22 subjects showed close correlations with left ventricular chamber radii, length, volume and wall thickness determined from biplane angiograms over the range of stroke volume [19].
  • Treatment of the patient's plasma in vitro with protamine or barium sulfate normalized the thrombin time [20].
  • Epicardial wall motion was analyzed using biplane cineradiography with frame to frame measurements of distances between pairs of radiopaque epicardial markers placed at the time of previous cardiac surgery [21].
  • The relation between acute disproportionate infarct dilation and late postinfarct left ventricular remodeling was examined by implanting multiple radiopaque epicardial markers in the left ventricle of eight dogs and determining regional surface deformation after acute and chronic transmural infarction [22].

Anatomical context of Baritop


Associations of Baritop with other chemical compounds


Gene context of Baritop


Analytical, diagnostic and therapeutic context of Baritop

  • Forty-four severely constipated women and 16 (8 female, 8 male) asymptomatic volunteers underwent assessment of colon function by (a) clinical examination, (b) rectosigmoid intraluminal pressure recording, (c) colonic transit utilizing radiopaque markers, (d) anorectal manometry, and (e) rectosigmoid electrical activity [38].
  • Using a water-cushion lithotripter at high-power setting, selected patients with solitary gallbladder stones with a radiopaque rim may be treated safely and successfully by shock-wave lithotripsy combined with bile acid dissolution therapy [10].
  • Although most of the liquid component of the meal, labeled with 111In, emptied during the first hour (as assessed simultaneously by radionuclide scintigraphy), few radiopaque markers emptied from the stomach during the first 2 h after the meal [5].
  • Fluid therapy in severe systemic reaction to radiopaque dye [39].
  • We therefore investigated the immediate and short-term effects on arterial patency of a new, radiopaque, balloon-expandable coil stent in normal coronary arteries of pigs [40].


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  2. Pathogenesis of ascites in mice with peritoneal carcinomatosis. Fastaia, J., Dumont, A.E. J. Natl. Cancer Inst. (1976) [Pubmed]
  3. Influence of gallstones and ursodeoxycholic acid therapy on gallbladder emptying. Forgacs, I.C., Maisey, M.N., Murphy, G.M., Dowling, R.H. Gastroenterology (1984) [Pubmed]
  4. Occult radiopaque jaw lesions in familial adenomatous polyposis coli and hereditary nonpolyposis colorectal cancer. Offerhaus, G.J., Levin, L.S., Giardiello, F.M., Krush, A.J., Welsh, S.B., Booker, S.V., Hasler, J.F., McKusick, V.A., Yardley, J.H., Hamilton, S.R. Gastroenterology (1987) [Pubmed]
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  6. Recovery of fasted and fed gastrointestinal motility after open versus laparoscopic cholecystectomy in dogs. Hotokezaka, M., Combs, M.J., Mentis, E.P., Schirmer, B.D. Ann. Surg. (1996) [Pubmed]
  7. Tagging-based, electronically cleansed CT colonography: evaluation of patient comfort and image readability. Zalis, M.E., Perumpillichira, J.J., Magee, C., Kohlberg, G., Hahn, P.F. Radiology. (2006) [Pubmed]
  8. Urinary stone size: comparison of abdominal plain radiography and noncontrast CT measurements. Parsons, J.K., Lancini, V., Shetye, K., Regan, F., Potter, S.R., Jarrett, T.W. J. Endourol. (2003) [Pubmed]
  9. Duodenum as a immediate brake to gastric outflow: a videofluoroscopic and manometric assessment. Rao, S.S., Lu, C., Schulze-Delrieu, K. Gastroenterology (1996) [Pubmed]
  10. Noninvasive therapy of gallbladder calculi with a radiopaque rim. Sackmann, M., Pauletzki, J., Delius, M., Holl, J., Neubrand, M., Sauerbruch, T., Paumgartner, G. Gastroenterology (1992) [Pubmed]
  11. Delayed gastrointestinal transit times in anorexia nervosa and bulimia nervosa. Kamal, N., Chami, T., Andersen, A., Rosell, F.A., Schuster, M.M., Whitehead, W.E. Gastroenterology (1991) [Pubmed]
  12. Gastric emptying of an indigestible solid in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis. Brown-Cartwright, D., Smith, H.J., Feldman, M. Gastroenterology (1988) [Pubmed]
  13. Effects of metrizamide, a new nonionic contrast medium, on cardiac function during coronary angiography in the dog. Trägårdh, G., Lynch, P.R., Vinciguerra, T. Radiology. (1975) [Pubmed]
  14. Coronary stenting (Cordis) without anticoagulation. Park, S.W., Park, S.J., Hong, M.K., Kim, J.J., Cho, S.Y., Jang, Y.S., Kim, K.B., Kim, K.S., Oh, D.J., Oh, B.H., Kang, J.C. Am. J. Cardiol. (1997) [Pubmed]
  15. Crohn's disease evaluation: comparison of contrast-enhanced MR imaging and single-phase helical CT scanning. Low, R.N., Francis, I.R., Politoske, D., Bennett, M. Journal of magnetic resonance imaging : JMRI. (2000) [Pubmed]
  16. Papillary muscle-left ventricular wall "complex". Komeda, M., Glasson, J.R., Bolger, A.F., Daughters, G.T., Ingels, N.B., Miller, D.C. J. Thorac. Cardiovasc. Surg. (1997) [Pubmed]
  17. The temporalis: blood supply and innervation. Burggasser, G., Happak, W., Gruber, H., Freilinger, G. Plast. Reconstr. Surg. (2002) [Pubmed]
  18. Influence of food and marker length on gastric emptying of indigestible radiopaque markers in healthy humans. Smith, H.J., Feldman, M. Gastroenterology (1986) [Pubmed]
  19. Quantitative measurement of left ventricular volumes in man from radiopaque epicardial markers. Vine, D.L., Dodge, H.T., Frimer, M., Stewart, D.K., Caldwell, J. Circulation (1976) [Pubmed]
  20. Isolation of a heparin-like anticoagulant from the plasma of a patient with metastatic bladder carcinoma. Tefferi, A., Owen, B.A., Nichols, W.L., Witzig, T.E., Owen, W.G. Blood (1989) [Pubmed]
  21. Epicardial wall motion and left ventricular function during coronary graft angioplasty in humans. Jaski, B.E., Serruys, P.W. J. Am. Coll. Cardiol. (1985) [Pubmed]
  22. Disproportionate epicardial dilation after transmural infarction of the canine left ventricle: acute and chronic differences. Kass, D.A., Maughan, W.L., Ciuffo, A., Graves, W., Healy, B., Weisfeldt, M.L. J. Am. Coll. Cardiol. (1988) [Pubmed]
  23. Percutaneous pancreatography: case report and presentation of technique. Zimmon, D.S., Panke, W.F., Clemett, A.R. Gastroenterology (1979) [Pubmed]
  24. Where do all the tablets go? Evans, K.T., Roberts, G.M. Lancet (1976) [Pubmed]
  25. Mitral annular dilatation and papillary muscle dislocation without mitral regurgitation in sheep. Green, G.R., Dagum, P., Glasson, J.R., Daughters, G.T., Bolger, A.F., Foppiano, L.E., Berry, G.J., Ingels, N.B., Miller, D.C. Circulation (1999) [Pubmed]
  26. Impact of compensatory enlargement of atherosclerotic coronary arteries on angiographic assessment of coronary artery disease. Stiel, G.M., Stiel, L.S., Schofer, J., Donath, K., Mathey, D.G. Circulation (1989) [Pubmed]
  27. Enhanced regional deformation at the anterior papillary muscle insertion site after chordal transsection. Takayama, Y., Holmes, J.W., LeGrice, I., Covell, J.W. Circulation (1996) [Pubmed]
  28. Loss of metastatic and primary tumor factor X activator capabilities by Lewis lung carcinoma cells cultured in vitamin K-dependent protein deficient serum. Fasco, M.J., Eagan, G.E., Wilson, A.C., Gierthy, J.F., Lincoln, D.L. Cancer Res. (1988) [Pubmed]
  29. Purification and properties of human lymphocyte activating factor (LAF). Blyden, G., Handschumacher, R.E. J. Immunol. (1977) [Pubmed]
  30. Effect of delayed esophageal transit on acetaminophen absorption. Channer, K.S., Roberts, C.J. Clin. Pharmacol. Ther. (1985) [Pubmed]
  31. Embolization with radiopaque microbeads of polyacrylonitrile hydrogel: evaluation in swine. Gobin, Y.P., Viñuela, F., Vinters, H.V., Ji, C., Chow, K. Radiology. (2000) [Pubmed]
  32. Purification and biochemical characterization of CP4 (SP-D), a collagenous surfactant-associated protein. Persson, A., Chang, D., Rust, K., Moxley, M., Longmore, W., Crouch, E. Biochemistry (1989) [Pubmed]
  33. The effect of fibroblast growth factor-2 on the osteoinductive activity of recombinant human bone morphogenetic protein-2 in rat muscle. Fujimura, K., Bessho, K., Okubo, Y., Kusumoto, K., Segami, N., Iizuka, T. Arch. Oral Biol. (2002) [Pubmed]
  34. Digital subtraction intravenous left ventricular angiography: comparison with conventional intraventricular angiography. Goldberg, H.L., Borer, J.S., Moses, J.W., Fisher, J., Cohen, B., Skelly, N.T. J. Am. Coll. Cardiol. (1983) [Pubmed]
  35. Calcification of basal ganglia and cerebellar roof nuclei in mentally defective patient with hidrotic ectodermal dysplasia. Analysis of intracranial concretions by electon microprobe. Copeland, D.D., Lamb, W.A., Klintworth, G.K. Neurology (1977) [Pubmed]
  36. Defecography commode. Bernier, P., Stevenson, G.W., Shorvon, P. Radiology. (1988) [Pubmed]
  37. A new surgical prosthesis for hiatal hernia repair: radiographic appearance. Lewis, R.A., Angelchik, J.P., Cohen, R. Radiology. (1980) [Pubmed]
  38. Colonic and anorectal motility in young women with severe idiopathic constipation. Waldron, D., Bowes, K.L., Kingma, Y.J., Cote, K.R. Gastroenterology (1988) [Pubmed]
  39. Fluid therapy in severe systemic reaction to radiopaque dye. Obeid, A.I., Johnson, L., Potts, J., Mookherjee, S., Eich, R.H. Ann. Intern. Med. (1975) [Pubmed]
  40. Coronary stenting with a new, radiopaque, balloon-expandable endoprosthesis in pigs. van der Giessen, W.J., Serruys, P.W., van Beusekom, H.M., van Woerkens, L.J., van Loon, H., Soei, L.K., Strauss, B.H., Beatt, K.J., Verdouw, P.D. Circulation (1991) [Pubmed]
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