Disease relevance of Bronchopulmonary Sequestration

• Thus, our data show for the first time that platelets do express functional levels of TLR4, which contribute to thrombocytopenia through neutrophil-dependent pulmonary sequestration in response to LPS [1].
• These included seven patients with bronchogenic cysts, two with intralobar pulmonary sequestrations, one with scimitar syndrome, and one with bronchial atresia [2].
• Combined lung and vascular anomalies include the hypogenetic lung (scimitar) syndrome and bronchopulmonary sequestration, both intralobar and extralobar [3].
• The radiologist's involvement in dealing with congenital lobar emphysema, congenital cystic adenomatoid malformation, extralobar pulmonary sequestration, and congenital diaphragmatic hernia has changed [4].
• Dynamic single photon emission computed tomography with xenon-133 gas in a 29-year-old male patient showed xenon-133 retention within an intralobar bronchopulmonary sequestration (BPS) with a focal hyperlucent lung area on CT [5].

High impact information on Bronchopulmonary Sequestration

• Pentoxifylline (PTX) reduced pulmonary sequestration of neutrophils and neutrophil-dependent lung injury in several experimental settings but has never been tested in IR models [6].
• The congenital lung anomalies were intra-abdominal pulmonary sequestration associated with congenital cystic adenomatoid malformation (CCAM), intrathoracic sequestration again with features of CCAM, an intrathoracic sequestration associated with a congenital diaphragmatic hernia, and 2 Stocker type II intrathoracic CCAMs [7].
• CONCLUSIONS: Significant pulmonary sequestration and slow release of propofol into arterial circulation when administered in lipid-free vehicle accounts for the lower peak arterial concentration and sluggish arterial kinetics relative to that observed with the emulsion formulation [8].
• Pulmonary sequestration of amiodarone and desethylamiodarone [9].
• Reversible dilated cardiomyopathy after lobectomy for pulmonary sequestration [10].

Chemical compound and disease context of Bronchopulmonary Sequestration

• Scimitar sign with normal pulmonary venous drainage and systemic arterial supply. Scimitar syndrome or bronchopulmonary sequestration [11]?
• It may be expected that a temporary pulmonary sequestration of fentanyl and alfentanil has considerable impact on the time course of their pharmacological effects, on the time necessary to reach their maximum effect and on the intensity and (in case of fentanyl) the duration of these effects [12].
• We hypothesized that 3'-sulfated Lewis(a) (SuLa), a potent ligand for the selectin adhesion molecules, may have a beneficial effect on I/R lung injury, as measured by the filtration coefficient (K(fc)), and reduce pulmonary sequestration of PMN as assessed by the lung myeloperoxidase (MPO) activity [13].
• Intralobar bronchopulmonary sequestration: evidence of air trapping shown by dynamic xenon-133 SPECT [5].
• Quantitative serial scintigraphic scanning showed significant (35%) pulmonary sequestration of autologous erythrocytes labeled with sodium chromate Cr51 [14].

Anatomical context of Bronchopulmonary Sequestration

• Major components of CPVS include hypogenetic lung, partial anomalous pulmonary venous return (this and the former are two of the most constantly occurring components), absence of a pulmonary artery, pulmonary sequestration, systemic arterialization of the lung, absence of the inferior vena cava, and accessory diaphragm [15].

Gene context of Bronchopulmonary Sequestration

• Therefore, endotoxin-induced TNF-alpha generation in lungs significantly contributes to pulmonary sequestration of PMN [16].
• A case of intralobar pulmonary sequestration with calcification and elevated serum values of carcinoembryonic antigen and carbohydrate antigen 19-9 [17].
• Association of bronchopulmonary sequestration with expression of the homeobox protein Hoxb-5 [18].
• CONCLUSION: Pulmonary 3D TOF MRA using breath holding and a contrast medium is useful in demonstrating proximal pulmonary vasculature and pulmonary sequestration [19].
• Intralobar pulmonary sequestration presenting increased serum CA19-9 and CA125 [20].

Analytical, diagnostic and therapeutic context of Bronchopulmonary Sequestration

• Early prenatal diagnosis of bronchopulmonary sequestration with associated diaphragmatic hernia [21].

References