Disease relevance of Oesophagostomum

• Treatment of mixed Oesophagostomum and hookworm infection: effect of albendazole, pyrantel pamoate, levamisole and thiabendazole [1].

High impact information on Oesophagostomum

• Levamisole receptor channel currents in muscle patches from levamisole-sensitive and levamisole-resistant isolates of the parasitic nematode Oesophagostomum dentatum were compared [2].
• Screening for nucleotide variations in ribosomal DNA arrays of Oesophagostomum bifurcum by polymerase chain reaction-coupled single-strand conformation polymorphism [3].
• A male-specific (cysteine-rich) protein of Oesophagostomum dentatum (Strongylida) with structural characteristics of a serine protease inhibitor containing two trypsin inhibitor-like domains [4].
• Living and fixed specimen of Oesophagostomum dentatum were labelled in situ with serum antibodies or a panel of biotin-labelled lectins [5].
• Changes in antigen and glycoprotein patterns during the development of Oesophagostomum dentatum [6].

Biological context of Oesophagostomum

• Sequence variations in the introns of the triosephosphate isomerase genes of Oesophagostomum dentatum and O. quadrispinulatum [7].
• Different phenotypes have been observed in the G6PD isoenzymatic pattern activity in males and females of Oesophagostomum venulosum [8].

Associations of Oesophagostomum with chemical compounds

• The kinetic disposition of pyrantel citrate and pamoate and their efficacy against pyrantel-resistant Oesophagostomum dentatum in pigs [9].
• The influence of high- and low-fibre diets on the activity of piperazine against Oesophagostomum spp. in pigs [10].
• When tested against pyrantel-resistant adult Oesophagostomum dentatum the mean efficacy of pyrantel citrate was only 23%, whereas the efficacy of the lesser absorbed pyrantel pamoate was 75% [9].
• An in vivo dose-response study of fenbendazole against Oesophagostomum dentatum and Oesophagostomum quadrispinulatum in pigs [11].
• Heterogeneous levamisole receptors: a single-channel study of nicotinic acetylcholine receptors from Oesophagostomum dentatum [12].

Gene context of Oesophagostomum

• O. venulosum was isolated from sheep and goat; G6PD and MDH isoenzymatic patterns discriminated this species from porcine species of Oesophagostomum [13].
• Degenerated primers were used to amplify DNA fragments of the triosephosphate isomerase (TPI) gene from complementary DNA (cDNA) and from genomic DNA of two species of porcine gastrointestinal nematodes, Oesophagostomum dentatum and O.quadrispinulatum [7].
• For clarification of the role of the Mpi locus encoding mannose-phosphate isomerase enzyme in determining resistance, genotyping of Oesophagostomum dentatum strains was performed using an isoelectrofocusing technique [14].
• Pigs in groups A and B were trickle infected with Oesophagostomum spp 3 times weekly throughout the study [15].
• Neutrophilic nodules in the intestinal walls of Japanese monkeys associated with the neutrophil chemotactic activity of larval extracts and secretions of Oesophagostomum aculeatum [16].

References