Disease relevance of Ileocecal Valve

• Effects of insulin-like growth factor-1 on Short bowel syndrome without ileocecal valve in rats [1].

High impact information on Ileocecal Valve

• Sucrase and lactase activities were found to be highest in the jejunum, whereas glucoamylase activity rose steadily and reached its highest activity near the ileocecal valve [2].
• Glutaraldehyde cross-linked collagen was injected through the efferent limb at the level of the ileocecal valve [3].
• In the combined categories of 15 to 38 cm jejunoileum without the ileocecal valve and less than 15 cm jejunoileum with and without the ileocecal valve, seven (70%) of 10 have survived, compared with none (0%) of 16 before 1972; three of these discontinued parenteral nutrition [4].
• CONCLUSIONS: The peak concentrations of PYY in the ileal mucosa are found 20 to 25 cm proximal to the ileocecal valve [5].
• Small bowel was exteriorized, an enterotomy was performed, and an Olympus CL-100L colonoscope was inserted and advanced proximally to the stomach and distally to the ileocecal valve [6].

Anatomical context of Ileocecal Valve

• When the ileocecal valve and the right colon were preserved, malabsorption was transient and moderate and had no prejudicial nutritional effect (fecal fat: 8.8 +/- 1.8 g/24 h in resections sparing the 2 distal bowel loops, and 16.2 +/- 4.8 g/24 h in resections including the distal ileum; mean +/- SEM) [7].
• Insulin-like growth factor-1 (IGF-1) can promote enterocyte proliferation which may be beneficial to postoperative conditions after massive small bowel resection (SBR) including the ileocecal valve (ICV) [1].

Associations of Ileocecal Valve with chemical compounds

• Ileocecal valve resistance augmentation using glutaraldehyde cross-linked collagen: a canine model for endoscopic salvage of the leaking Indiana reservoir [8].
• All dogs received infusions (in random order) of intraduodenal corn oil (Lipomul) (3 ml/kg/hr) and intravenous calcium chloride (0.36 mmol/kg intravenous bolus, followed by 0.36 mmol/kg/hr infusion) before and 6 weeks after resection of the distal two thirds of the small bowel with preservation of the ileocecal valve [9].
• On the day of killing, 0.1 mL of latex beads solution was injected into a 1-cm length of ileal loop, within 10 cm of the ileocecal valve [10].
• Warfarin-induced intramural haematoma of the ileocecal valve with obstruction [11].
• A major function of the mammalian colon is the absorption of water and electrolytes from the luminal contents that enter through the ileocecal valve [12].

Gene context of Ileocecal Valve

• The development of neighboring anatomical structures such as the ileocecal valve is not affected by Fgf10/Fgfr2b invalidation [13].
• Total colonoscopy on March 17th showed multiple aphthoid lesions and friable mucosa from the terminal ileum to the rectum and a shallow ulcer on the ileocecal valve [14].
• The aim of the present study was to examine what length of intussusception-like nipple valve (INV) should be constructed in order to restore the hydrostatic characteristics of the normal ileocecal valve [15].
• The cancer in the ileocecal valve is derived from the colonic part of the valve which acquired the additional genetic change of p53 mutation [16].

References