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MeSH Review

Gait Ataxia

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Disease relevance of Gait Ataxia


High impact information on Gait Ataxia

  • In view of its afferent and efferent connections, destruction of the LRT probably contributes to gait ataxia in individuals suffering from SCA3 [6].
  • When rats received pyridoxine in doses large enough to cause neuropathy in humans, the animals developed gait ataxia that subsided after the toxin was withdrawn [7].
  • GDNF and IGF-I trophic factors delay hereditary Purkinje cell degeneration and the progression of gait ataxia [8].
  • Piracetam was demonstrated to be highly effective on tandem gait and gait ataxia in daily doses of 60 g [9].
  • Gait ataxia during omeprazole therapy [10].

Gene context of Gait Ataxia


  1. Frequency and phenotypic spectrum of ataxia with oculomotor apraxia 2: a clinical and genetic study in 18 patients. Le Ber, I., Bouslam, N., Rivaud-Péchoux, S., Guimarães, J., Benomar, A., Chamayou, C., Goizet, C., Moreira, M.C., Klur, S., Yahyaoui, M., Agid, Y., Koenig, M., Stevanin, G., Brice, A., Dürr, A. Brain (2004) [Pubmed]
  2. Cerebellar ataxia associated with heteroallelic ceruloplasmin gene mutation. Miyajima, H., Kono, S., Takahashi, Y., Sugimoto, M., Sakamoto, M., Sakai, N. Neurology (2001) [Pubmed]
  3. Heart hypertrophy and function are improved by idebenone in Friedreich's ataxia. Rustin, P., Rötig, A., Munnich, A., Sidi, D. Free Radic. Res. (2002) [Pubmed]
  4. A multicentre comparative trial of sodium valproate and carbamazepine in paediatric epilepsy. The Paediatric EPITEG Collaborative Group. Verity, C.M., Hosking, G., Easter, D.J. Developmental medicine and child neurology. (1995) [Pubmed]
  5. Sicca syndrome and anti-SSA/Ro antibodies in patients with suspected or definite multiple sclerosis. Montecucco, C., Franciotta, D.M., Caporali, R., DeGennaro, F., Citterio, A., Melzi d'Eril, G.V. Scand. J. Rheumatol. (1989) [Pubmed]
  6. Spinocerebellar ataxia type 3 (Machado-Joseph disease): severe destruction of the lateral reticular nucleus. Rüb, U., de Vos, R.A., Schultz, C., Brunt, E.R., Paulson, H., Braak, H. Brain (2002) [Pubmed]
  7. Pyridoxine neuropathy in rats: specific degeneration of sensory axons. Windebank, A.J., Low, P.A., Blexrud, M.D., Schmelzer, J.D., Schaumburg, H.H. Neurology (1985) [Pubmed]
  8. GDNF and IGF-I trophic factors delay hereditary Purkinje cell degeneration and the progression of gait ataxia. Tolbert, D.L., Clark, B.R. Exp. Neurol. (2003) [Pubmed]
  9. High-dose piracetam is effective on cerebellar ataxia in patient with cerebellar cortical atrophy. Vural, M., Ozekmekçi, S., Apaydin, H., Altinel, A. Mov. Disord. (2003) [Pubmed]
  10. Gait ataxia during omeprazole therapy. Varona, L., Ruiz, J., Zarranz, J.J. The Annals of pharmacotherapy. (1996) [Pubmed]
  11. Congestive heart failure and cardiac thrombus as first presentations of Friedreich ataxia. Tsao, C.Y., Lo, W.D., Craenen, J. Pediatric neurology. (1992) [Pubmed]
  12. Study of a family with progressive ataxia, tremor and severe distal amyotrophy. Bouchard, J., Bedard, P., Bouchard, R. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (1980) [Pubmed]
  13. Wernicke's encephalopathy: unusual contrast enhancement revealed by magnetic resonance imaging. Kavuk, I., Agelink, M.W., Gaertner, T., Kastrup, O., Doerfler, A., Maschke, M., Diener, H.C. Eur. J. Med. Res. (2003) [Pubmed]
  14. Delayed encephalopathy after carbon monoxide intoxication--long-term prognosis and correlation of clinical manifestations and neuroimages. Hsiao, C.L., Kuo, H.C., Huang, C.C. Acta neurologica Taiwanica. (2004) [Pubmed]
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