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MeSH Review

Cerebellar Diseases

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Disease relevance of Cerebellar Diseases


Psychiatry related information on Cerebellar Diseases


High impact information on Cerebellar Diseases


Chemical compound and disease context of Cerebellar Diseases


Biological context of Cerebellar Diseases

  • Two patients sharing a novel mutation of the CACNA1A gene for P/Q calcium channels showed significant slowing of adducting saccades compared with normal subjects or patients with cerebellar disease [17].

Anatomical context of Cerebellar Diseases


Gene context of Cerebellar Diseases


Analytical, diagnostic and therapeutic context of Cerebellar Diseases


  1. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Gatei, M., Young, D., Cerosaletti, K.M., Desai-Mehta, A., Spring, K., Kozlov, S., Lavin, M.F., Gatti, R.A., Concannon, P., Khanna, K. Nat. Genet. (2000) [Pubmed]
  2. Neurotoxicity associated with systemic high-dose cytosine arabinoside. Nand, S., Messmore, H.L., Patel, R., Fisher, S.G., Fisher, R.I. J. Clin. Oncol. (1986) [Pubmed]
  3. The MAZ protein is an autoantigen of Hodgkin's disease and paraneoplastic cerebellar dysfunction. Bataller, L., Wade, D.F., Graus, F., Rosenfeld, M.R., Dalmau, J. Ann. Neurol. (2003) [Pubmed]
  4. Alpha 1-antichymotrypsin is present in diffuse senile plaques. A comparative study of beta-protein and alpha 1-antichymotrypsin immunostaining in the Alzheimer brain. Shoji, M., Hirai, S., Yamaguchi, H., Harigaya, Y., Ishiguro, K., Matsubara, E. Am. J. Pathol. (1991) [Pubmed]
  5. Hereditary adult-onset Alexander's disease with palatal myoclonus, spastic paraparesis, and cerebellar ataxia. Schwankhaus, J.D., Parisi, J.E., Gulledge, W.R., Chin, L., Currier, R.D. Neurology (1995) [Pubmed]
  6. Smallpox vaccination and adverse reactions. Guidance for clinicians. Cono, J., Casey, C.G., Bell, D.M. MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. (2003) [Pubmed]
  7. Delayed cerebellar disease and death after accidental exposure to dimethylmercury. Nierenberg, D.W., Nordgren, R.E., Chang, M.B., Siegler, R.W., Blayney, M.B., Hochberg, F., Toribara, T.Y., Cernichiari, E., Clarkson, T. N. Engl. J. Med. (1998) [Pubmed]
  8. Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia. Walter, J.T., Alviña, K., Womack, M.D., Chevez, C., Khodakhah, K. Nat. Neurosci. (2006) [Pubmed]
  9. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome. Koekkoek, S.K., Yamaguchi, K., Milojkovic, B.A., Dortland, B.R., Ruigrok, T.J., Maex, R., De Graaf, W., Smit, A.E., VanderWerf, F., Bakker, C.E., Willemsen, R., Ikeda, T., Kakizawa, S., Onodera, K., Nelson, D.L., Mientjes, E., Joosten, M., De Schutter, E., Oostra, B.A., Ito, M., De Zeeuw, C.I. Neuron (2005) [Pubmed]
  10. Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice. Feddersen, R.M., Ehlenfeldt, R., Yunis, W.S., Clark, H.B., Orr, H.T. Neuron (1992) [Pubmed]
  11. Cerebellar dysfunction after acute carbon tetrachloride poisoning. Johnson, B.P., Meredith, T.J., Vale, J.A. Lancet (1983) [Pubmed]
  12. Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction? Atchison, W.D. Trends Pharmacol. Sci. (2005) [Pubmed]
  13. Cytarabine and neurologic toxicity. Baker, W.J., Royer, G.L., Weiss, R.B. J. Clin. Oncol. (1991) [Pubmed]
  14. Effects of ketamine on leading saccades during smooth-pursuit eye movements may implicate cerebellar dysfunction in schizophrenia. Avila, M.T., Weiler, M.A., Lahti, A.C., Tamminga, C.A., Thaker, G.K. The American journal of psychiatry. (2002) [Pubmed]
  15. Hypoglycemia-induced cerebellar dysfunction and quantitative positron emission tomography study. Kim, D.E., Park, S.H., Kim, S.K., Nam, H.W., Lee, Y.S., Chung, J.K., Roh, J.K. Neurology (2000) [Pubmed]
  16. Double-blind crossover study with levorotatory form of hydroxytryptophan in patients with degenerative cerebellar diseases. Wessel, K., Hermsdörfer, J., Deger, K., Herzog, T., Huss, G.P., Kömpf, D., Mai, N., Schimrigk, K., Wittkämper, A., Ziegler, W. Arch. Neurol. (1995) [Pubmed]
  17. Internuclear ophthalmoparesis in episodic ataxia type 2. Rucker, J.C., Jen, J., Stahl, J.S., Natesan, N., Baloh, R.W., Leigh, R.J. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
  18. Purkinje cell degeneration, a new neurological mutation in the mouse. Mullen, R.J., Eicher, E.M., Sidman, R.L. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
  19. X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndrome. Cason, A.L., Ikeguchi, Y., Skinner, C., Wood, T.C., Holden, K.R., Lubs, H.A., Martinez, F., Simensen, R.J., Stevenson, R.E., Pegg, A.E., Schwartz, C.E. Eur. J. Hum. Genet. (2003) [Pubmed]
  20. Sodium valproate in the treatment of cerebellar disorders. Neophytides, A.N., Teychenne, P.F., Pfeiffer, R.F., Calne, D.B. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (1979) [Pubmed]
  21. Neurological complications of 5-fluorouracil chemotherapy: case report and review of the literature. Bygrave, H.A., Geh, J.I., Jani, Y., Glynne-Jones, R. Clinical oncology (Royal College of Radiologists (Great Britain)) (1998) [Pubmed]
  22. Superficial siderosis of the central nervous system: a neglected cause of sensorineural hearing loss. Parnes, S.M., Weaver, S.A. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. (1992) [Pubmed]
  23. Novel CACNA1A mutation causes febrile episodic ataxia with interictal cerebellar deficits. Subramony, S.H., Schott, K., Raike, R.S., Callahan, J., Langford, L.R., Christova, P.S., Anderson, J.H., Gomez, C.M. Ann. Neurol. (2003) [Pubmed]
  24. Fast cerebellar oscillation associated with ataxia in a mouse model of Angelman syndrome. Cheron, G., Servais, L., Wagstaff, J., Dan, B. Neuroscience (2005) [Pubmed]
  25. Cerebellar dysfunction is associated with overexpression of proinflammatory cytokine genes in lupus. Tomita, M., Holman, B.J., Williams, L.S., Pang, K.C., Santoro, T.J. J. Neurosci. Res. (2001) [Pubmed]
  26. Decrease in cerebellin and corticotropin-releasing hormone in the cerebellum of olivopontocerebellar atrophy and Shy-Drager syndrome. Mizuno, Y., Takahashi, K., Totsune, K., Ohneda, M., Konno, H., Murakami, O., Satoh, F., Sone, M., Takase, S., Itoyama, Y. Brain Res. (1995) [Pubmed]
  27. Anticerebellar antibodies in neurologically normal patients with ovarian neoplasms. Brashear, H.R., Greenlee, J.E., Jaeckle, K.A., Rose, J.W. Neurology (1989) [Pubmed]
  28. mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning. Kishimoto, Y., Fujimichi, R., Araishi, K., Kawahara, S., Kano, M., Aiba, A., Kirino, Y. Eur. J. Neurosci. (2002) [Pubmed]
  29. Double-blind crossover study with dolasetron mesilate, a 5-HT3 receptor antagonist in cerebellar syndrome secondary to multiple sclerosis. Monaca-Charley, C., Stojkovic, T., Duhamel, A., De Seze, J., Ferriby, D., Vermersch, P. J. Neurol. (2003) [Pubmed]
  30. Isoelectric focusing and electrophoresis of the CSF proteins in tremor of different origins. Stibler, H., Kjellin, K.G. J. Neurol. Sci. (1976) [Pubmed]
  31. Cerebral vasculitis after interleukin-2 therapy for renal cell carcinoma. Michel, M., Vincent, F., Sigal, R., Damaj, G., Bensousan, T.A., Leclercq, B., Escudier, B. Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy. (1995) [Pubmed]
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