Disease relevance of Encephalomyelitis, Western Equine

• The studies presented here demonstrate that helix I can be functionally replaced by the corresponding sequence of a related alphavirus, western equine encephalitis virus, and also by an unrelated sequence from the yeast transcription activator, GCN4, that was previously shown to form a dimeric coiled coil [1].
• Sera from humans with serologically confirmed eastern equine encephalitis, western equine encephalitis, Pogosta (Ockelbo), Mayaro, Ross River, and chikungunya virus infections were tested by immunoglobulin M (IgM) antibody capture enzyme immunoassay [2].
• Louis encephalitis and western equine encephalomyelitis, did not induce CO2 sensitivity in Ae. dorsalis and Cx. tarsalis [3].
• Sera from horses and human beings with clinically diagnosed western equine encephalitis (WEE) virus infections were tested for hemagglutination-inhibition (HI), complement-fixation (CF), and neutralizing (N) antibody to WEE virus [4].
• Pregnant Rhesus monkeys were infected via instillation of influenza, mumps and western equine encephalomyelitis viruses respectively into the amniotic sacs at approximately 90 days gestation to determine if fetal infections would occur [5].

High impact information on Encephalomyelitis, Western Equine

• After brain biopsy and administration of vidarabine, the patient's condition improved but was ultimately diagnosed as a case of western equine encephalitis [6].
• Biochemical and biological characteristics of epitopes on the E1 glycoprotein of western equine encephalitis virus [7].
• Ribavirin or certain analogues have no detectable in vivo activity against arboviral encephalitic infections caused by Venezuelan or Western Equine Encephalitis or Semliki Forest Viruses [8].
• Nucleoside triphosphate phosphohydrolase produced in BHK cells infected with western equine encephalitis virus is probably associated with the 82K dalton nonstructural polypeptide [9].
• The E1 and E2 glycoproteins of Western Equine Encephalitis (WEE) are candidate antigens for WEE subunit vaccine development [10].

Chemical compound and disease context of Encephalomyelitis, Western Equine

• Effect of cordycepin on the replication of western equine encephalitis virus [11].
• Development of a biotin mimic tagged ScFv antibody against western equine encephalitis virus: bacterial expression and refolding [12].
• Cordycepin (3'-deoxyadenosine) inhibited viral RNA synthesis in the replication of western equine encephalitis virus, thereby causing a reduction of virus production [11].
• Effect of cycloheximide on the replication of western equine encephalitis virus [13].
• Tebrofen inhibited the replication of western equine encephalomyelitis (WEE) virus in multicycle experiments in chick embryo cell cell cultures [14].

Analytical, diagnostic and therapeutic context of Encephalomyelitis, Western Equine

• Immunosuppression of house finches was attempted by blood feeding Culex tarsalis Coquillett mosquitoes or by injecting birds with the corticosteroid dexamethasone or the immunosuppressant drug cyclophosphamide before and after inoculation with western equine encephalomyelitis or St [15].

References