High impact information on Solidago

• Goldenrod, Solidago canadensis, is unusual in that it produces both enantiomers of germacrene D [1].
• Two new (3, 4) and two known (1, 2) genuine acylated bisdesmosidic triterpenoid glycosides of polygalacic acid (2 beta, 3 beta, 16 alpha, 23-tetrahydroxyolean-12-en-28-oic acid) were isolated from the aerial parts, as well as from the roots, of Solidago virgaurea L. subsp. virgaurea [2].
• Solidago canadensis is typical of a flavonoid-rich herb and the effect of an aqueous ethanol extract on glutathione-S-transferase (GST) activity using HepG2 cells was compared with those of the flavonol quercetin and its glycosides quercitrin and rutin, found as major constituents [3].
• In-vitro effect of flavonoids from Solidago canadensis extract on glutathione S-transferase [3].
• Bioassay-directed fractionation of a methyl ethyl ketone extract of Solidago canadensis L [4].

Associations of Solidago with chemical compounds

• A new 3,28-bisdesmosidic triterpenoid glycoside was isolated from the mixture of deacylated saponins from the aerial parts of Solidago virgaurea [5].
• Simple reversed-phase HPLC with UV detection was used to determine quercetrin in five different Solidago virgaurea drugs [6].
• Hydrogen-donating ability and reducing power properties were used to define in vitro radical scavenging activity of Solidago extracts, but integral antioxidative capacity was determined by luminometry (Photochem), calculating the ascorbic acid equivalents [7].
• Biosynthesis of the sesquiterpene germacrene D in Solidago canadensis: 13C and (2)H labeling studies [8].
• Investigation of the roots and aerial parts of Solidago rugosa afforded the known diterpenes kolavenol, hardwickiic acid, (-)-kaur-16-en-19-oic acid, (+)-manool, (+)-3 beta-hydroxymanool, manoyl oxide and ent-abietic acid [9].

Gene context of Solidago

• Profiling of sesquiterpene hydrocarbons in extracts of goldenrod, Solidago canadensis, by GC-MS revealed the presence of both enantiomers of germacrene D and lesser amounts of germacrene A, alpha-humulene, and beta-caryophyllene [10].
• New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta [4].

References