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High impact information on Cleome


Biological context of Cleome

  • Enzymatic hydrolysis of the ethanol extract of Cleome chrysantha Decne., produced two non-volatile isothiocyanates, 4, 6-dimethyltetrahydro-1,3-oxazine-2-thione and N-(-4-methyl-sulphinyl-3-butenyl) isothiocyanate which was established by aniline and methanolic ammonia to give the stable form of phenyl thiourea [6].

Associations of Cleome with chemical compounds

  • Eighteen dammarane-type triterpenes were obtained from the whole plant of Cleome africana by means of cytotoxic bioassay-directed fractionation [7].
  • Preliminary tests indicate that the methanol extract of Cleome viscosa Linn. in doses of 200-400 mg/kg has significant psychopharmacological activity [8].
  • GC/MS analysis of the volatiles produced by the action of endogenous myrosinase in Cleome chrysantha Decne. herb, showed three major components, 1-isocyano-4-methyl benzene, gamma-muurolene and (cis) nerolidole (21.72%, 12.15% and 10.39%, respectively) [6].
  • The analgesic activity of methanol extract of Cleome viscosa, given orally at the doses of 100, 200, 400 mg/kg was evaluated for its analgesic activity in mice using the acetic acid-induced writhing and the tail flick, tail clip, tail immersion methods [9].


  1. Effect of Cleome arabica leaf extract, rutin and quercetin on soybean lipoxygenase activity and on generation of inflammatory eicosanoids by human neutrophils. Bouriche, H., Miles, E.A., Selloum, L., Calder, P.C. Prostaglandins Leukot. Essent. Fatty Acids (2005) [Pubmed]
  2. New cembranes from Cleome spinosa. Collins, D.O., Reynolds, W.F., Reese, P.B. J. Nat. Prod. (2004) [Pubmed]
  3. Cleogynol, a novel dammarane triterpenoid from Cleome gynandra. Das, P.C., Patra, A., Mandal, S., Mallick, B., Das, A., Chatterjee, A. J. Nat. Prod. (1999) [Pubmed]
  4. Antioxidant activity of Cleome arabica leaves extract. Selloum, L., Sebihi, L., Mekhalfia, A., Mahdadi, R., Senator, A. Biochem. Soc. Trans. (1997) [Pubmed]
  5. Phytochemical screening and antiviral activity of some medicinal plants from the island Soqotra. Mothana, R.A., Mentel, R., Reiss, C., Lindequist, U. Phytotherapy research : PTR. (2006) [Pubmed]
  6. Isothiocyanates in myrosinase treated herb extract of Cleome chrysantha decne. and their antimicrobial activities. Hashem, F.A., Wahba, H.E. Phytotherapy research : PTR. (2000) [Pubmed]
  7. Cytotoxic triterpenes from Cleome africana. Nagaya, H., Tobita, Y., Nagae, T., Itokawa, H., Takeya, K., Halim, A.F., Abdel-Halim, O.B. Phytochemistry (1997) [Pubmed]
  8. Studies on psychopharmacological effects of Cleome viscosa Linn. extract in rats and mice. Parimala Devi, B., Boominathan, R., Mandal, S.C. Phytotherapy research : PTR. (2004) [Pubmed]
  9. Studies on analgesic activity of Cleome viscosa in mice. Parimaladevi, B., Boominathan, R., Mandal, S.C. Fitoterapia (2003) [Pubmed]
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