Chemical Compound Review:
AG-G-81008 (5S,12R)-5,12-dihydroxyicosa- 6,8,10,14...
Synonyms:
AG-L-65953, KBioGR_000084, KBioSS_000084, CBiol_001847, CBiol_001893, ...
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- High-altitude pulmonary edema. Characteristics of lung lavage fluid. Schoene, R.B., Hackett, P.H., Henderson, W.R., Sage, E.H., Chow, M., Roach, R.C., Mills, W.J., Martin, T.R. JAMA (1986)
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- Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2. Bonventre, J.V., Huang, Z., Taheri, M.R., O'Leary, E., Li, E., Moskowitz, M.A., Sapirstein, A. Nature (1997)
- A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Yokomizo, T., Izumi, T., Chang, K., Takuwa, Y., Shimizu, T. Nature (1997)
- The PPARalpha-leukotriene B4 pathway to inflammation control. Devchand, P.R., Keller, H., Peters, J.M., Vazquez, M., Gonzalez, F.J., Wahli, W. Nature (1996)
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- Mechanisms underlying the protective effects of interleukin 1 in experimental nonsteroidal anti-inflammatory drug gastropathy. Wallace, J.L., Keenan, C.M., Cucala, M., Mugridge, K.G., Parente, L. Gastroenterology (1992)
- Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis. Wallace, J.L., Keenan, C.M., Gale, D., Shoupe, T.S. Gastroenterology (1992)
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- Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. de Haas, C.J., Veldkamp, K.E., Peschel, A., Weerkamp, F., Van Wamel, W.J., Heezius, E.C., Poppelier, M.J., Van Kessel, K.P., van Strijp, J.A. J. Exp. Med. (2004)
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- Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. Weller, C.L., Collington, S.J., Brown, J.K., Miller, H.R., Al-Kashi, A., Clark, P., Jose, P.J., Hartnell, A., Williams, T.J. J. Exp. Med. (2005)
- Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine. Loike, J.D., el Khoury, J., Cao, L., Richards, C.P., Rascoff, H., Mandeville, J.T., Maxfield, F.R., Silverstein, S.C. J. Exp. Med. (1995)
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- Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. Levy, B.D., Romano, M., Chapman, H.A., Reilly, J.J., Drazen, J., Serhan, C.N. J. Clin. Invest. (1993)
- The leukotriene B4 receptor functions as a novel type of coreceptor mediating entry of primary HIV-1 isolates into CD4-positive cells. Owman, C., Garzino-Demo, A., Cocchi, F., Popovic, M., Sabirsh, A., Gallo, R.C. Proc. Natl. Acad. Sci. U.S.A. (1998)
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- Leukotriene B4 plays a pivotal role in CD40-dependent activation of chronic B lymphocytic leukemia cells. Runarsson, G., Liu, A., Mahshid, Y., Feltenmark, S., Pettersson, A., Klein, E., Björkholm, M., Claesson, H.E. Blood (2005)
- Regulation of dendritic cell migration and adaptive immune response by leukotriene B4 receptors: a role for LTB4 in up-regulation of CCR7 expression and function. Del Prete, A., Shao, W.H., Mitola, S., Santoro, G., Sozzani, S., Haribabu, B. Blood (2007)
- Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. De Maria, R., Cifone, M.G., Trotta, R., Rippo, M.R., Festuccia, C., Santoni, A., Testi, R. J. Exp. Med. (1994)
- Intravenous infusion of tridocosahexaenoyl-glycerol emulsion into rabbits. Effects on leukotriene B4/5 production and fatty acid composition of plasma and leukocytes. Nakamura, N., Hamazaki, T., Yamazaki, K., Taki, H., Kobayashi, M., Yazawa, K., Ibuki, F. J. Clin. Invest. (1993)
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- Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages. Hubbard, R.C., Fells, G., Gadek, J., Pacholok, S., Humes, J., Crystal, R.G. J. Clin. Invest. (1991)
- Dietary supplementation with fish oil in ulcerative colitis. Stenson, W.F., Cort, D., Rodgers, J., Burakoff, R., DeSchryver-Kecskemeti, K., Gramlich, T.L., Beeken, W. Ann. Intern. Med. (1992)