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MeSH Review


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Disease relevance of Atropa


High impact information on Atropa


Biological context of Atropa


Associations of Atropa with chemical compounds

  • Responses of transformed root culture of Atropa belladonna to salicylic acid stress [8].
  • The aim of this study was to evaluate effects of low doses of Atropa belladonna L., Gelsemium sempervirens L. and Poumon histamine on stress-induced behavioral, immunological and gastric alterations [9].
  • In order to investigate the production of tropane alkaloids by hairy roots of Atropa baetica, transgenic for the gene h6h encoding the enzyme hyoscyamine 6beta-hydroxylase, solvent extraction with chloroform and with dichloromethane of the metabolites present in the liquid medium and in the root tissue was compared [10].
  • The complete amino acid sequences of [2Fe-2S] ferredoxin from Atropa belladonna and Hyoscyamus niger have been determined by automated Edman degradation of the entire S-carboxymethylcysteinyl proteins and of the peptides obtained by enzymatic digestion [7].

Analytical, diagnostic and therapeutic context of Atropa

  • This single-blind placebo-controlled study was designed to investigate the dose-dependent vagolytic and vagotonic effects after a single oral administration of Atropa belladonna tincture (ABT, 0.1 mg/ml alkaloid concentration, atropine/scopolamine = 20:1) [11].


  1. A comparative study of Atropa belladonna and atropine on an animal model of urinary retention. Tita, B., Bolle, P., Martinoli, L., Mazzanti, G., Silvestrini, B. Pharmacological research communications. (1988) [Pubmed]
  2. Putrescine N-methyltransferase in Solanum tuberosum L., a calystegine-forming plant. Stenzel, O., Teuber, M., Dräger, B. Planta (2006) [Pubmed]
  3. An Atropa belladonna hyoscyamine 6beta-hydroxylase gene is differentially expressed in the root pericycle and anthers. Suzuki, K., Yun, D.J., Chen, X.Y., Yamada, Y., Hashimoto, T. Plant Mol. Biol. (1999) [Pubmed]
  4. Alkaloids in plants and root cultures of Atropa belladonna overexpressing putrescine N-methyltransferase. Rothe, G., Hachiya, A., Yamada, Y., Hashimoto, T., Dräger, B. J. Exp. Bot. (2003) [Pubmed]
  5. Salicylic acid carboxyl methyltransferase induced in hairy root cultures of Atropa belladonna after treatment with exogeneously added salicylic acid. Fukami, H., Asakura, T., Hirano, H., Abe, K., Shimomura, K., Yamakawa, T. Plant Cell Physiol. (2002) [Pubmed]
  6. Development of a packed-column supercritical fluid chromatography/atmospheric pressure chemical-ionisation mass spectrometric technique for the analysis of atropine. Dost, K., Davidson, G. J. Biochem. Biophys. Methods (2000) [Pubmed]
  7. Amino acid sequences of ferredoxins from Atropa belladonna and Hyoscyamus niger: their similarities to those in other tropane-alkaloid-containing plants. Mino, Y., Yukita, M., Hiratsuka, N., Wariishi, H. Biol. Pharm. Bull. (2005) [Pubmed]
  8. Responses of transformed root culture of Atropa belladonna to salicylic acid stress. Lee, K.T., Hirano, H., Yamakawa, T., Kodama, T., Igarashi, Y., Shimomura, K. J. Biosci. Bioeng. (2001) [Pubmed]
  9. Neurotropic, immunological and gastric effects of low doses of Atropa belladonna L., Gelsemium sempervirens L. and Poumon histamine in stressed mice. Bousta, D., Soulimani, R., Jarmouni, I., Belon, P., Falla, J., Froment, N., Younos, C. Journal of ethnopharmacology. (2001) [Pubmed]
  10. Studies on tropane alkaloid extraction by volatile organic solvents: dichloromethane vs. chloroform. El Jaber-Vazdekis, N., Gutierrez-Nicolas, F., Ravelo, A.G., Zárate, R. Phytochemical analysis : PCA. (2006) [Pubmed]
  11. Bimodal dose-dependent effect on autonomic, cardiac control after oral administration of Atropa belladonna. Bettermann, H., Cysarz, D., Portsteffen, A., Kümmell, H.C. Autonomic neuroscience : basic & clinical. (2001) [Pubmed]
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