Disease relevance of Urinary Retention

• Each had two to five attacks over periods of 3 to 8 years, characterized by ascending paresthesias, urinary retention, sensory loss with a thoracic or cervical level, paraparesis, hyperreflexia, and bilateral Babinski signs [1].
• Transurethral laser ablation of the prostate gland was used to treat benign prostatic hyperplasia in 10 patients on warfarin anticoagulant therapy who had either significant clinical symptoms or who were in urinary retention [2].
• Complications in the holmium laser enucleation group included stress urinary incontinence in 4 cases, prostatic perforation in 1 and urinary retention in 1 [3].
• MATERIALS AND METHODS: Formalin fixed and frozen specimens of recurrent prostate cancer were obtained by transurethral resection from men with increasing serum level of prostate specific antigen in whom urinary retention developed [4].
• Conditions such as bacterial prostatitis and acute urinary retention also can falsely elevate the serum PSA level [5].

High impact information on Urinary Retention

• Aside from its high prevalence, the importance of DHIC is that it may present as urinary retention, may closely mimic prostatic outlet obstruction, may explain why past therapeutic trials for detrusor hyperreflexia have failed, and may necessitate a change in the current nosology of bladder dysfunction [6].
• Nicardipine and urinary retention [7].
• An epidemic of urinary retention caused by dimethylaminopropionitrile [8].
• An epidemic of urinary retention among workers in a polyurethane manufacturing plant was discovered in the spring of 1978 [8].
• Complications during treatment, such as extragenital lesions or urinary retention requiring catheterization, developed in four patients given placebo and in none given acyclovir [9].

Chemical compound and disease context of Urinary Retention

• Theophylline-induced urinary retention [10].
• Urinary retention as a possible complication of long-term diazepam abuse [11].
• Aggravated CNS depression with urinary retention secondary to baclofen administration [12].
• Development of urinary retention during treatment with clozapine and meclizine [13].
• Urinary retention as a result of administration of terfenadine [14].

Biological context of Urinary Retention

• When given intrathecally in increasing doses, both muscimol (1 to 10 micrograms) and baclofen (0.1 to 5 micrograms) produced a dose-dependent inhibition of micturition with progressive increases in bladder capacity and residual volume, and a decrease in micturition pressure ending with urinary retention and dribbling incontinence [15].
• CONCLUSION: Glycine infusions might improve the contractile responses of bladder smooth muscle after acute urinary retention by reducing oxidative damage and apoptosis [16].
• Although the effect of prostaglandin F2 alpha on bladder muscle contraction was short-lived, it seemed to enhance the restoration of bladder motor function with no serious side effects, and thus to be clinically useful in the treatment of post-operative urinary retention [17].
• CONCLUSION: A single intraoperative dose of i.v. ketorolac appears to be opioid dose sharing, to provide superior analgesia, and to decrease the frequency of urinary retention during the first 12 hours of postoperative pediatric PCA with morphine [18].

Anatomical context of Urinary Retention

• Although the urinary retention developed in both male and female mice, the increase in urethral resistance to urinary flow and the dilatation of posterior urethra were observed only in castrated male mice receiving E2 [19].
• The short-lived effect of IT alfentanil on lower urinary tract dynamics and the relaxation of the bladder neck allow for unobstructed micturition pathways and may avoid urinary retention [20].
• Acute urinary retention after gonadotropin-releasing hormone agonist treatment for leiomyomata uteri [21].
• OBJECTIVE: To investigate the effects of glycine on the recovery of bladder smooth muscle contractility after acute urinary retention [16].
• OBJECTIVE: In this study the authors investigated the possible effect of venlafaxine on urinary function in a series of 9 patients with urinary retention resulting from spinal cord lesions [22].

Gene context of Urinary Retention

• A 71-year-old man experienced gradually progressive leg weakness, urinary retention, and mild loss of sensation in dermatomes T8 through T12 bilaterally [23].
• We recently treated a number of patients with markedly elevated prostate specific antigen (PSA) levels associated with acute urinary retention in a post-cardiac surgery setting [24].
• Nerve sparing extravesical repair of bilateral vesicoureteral reflux: description of technique and evaluation of urinary retention [25].
• CONCLUSIONS: Alpha-blocker therapy seems to be a viable alternative to biofeedback in dysfunctional voiding in children with urinary retention to improve bladder emptying [26].
• Acute urinary retention associated with the use of cyclooxygenase-2 inhibitors [27].

Analytical, diagnostic and therapeutic context of Urinary Retention

• CONCLUSIONS: Prophylactic tamsulosin (0.8 mg/day) before prostate brachytherapy did not significantly affect urinary retention rates, but had a positive effect on urinary morbidity at Week 5 after PI [28].
• PURPOSE: A randomized controlled study was done to evaluate the efficacy of the self-reinforced polyglycolic acid spiral stent compared to a suprapubic catheter, and combined suprapubic and indwelling catheters in the prevention of urinary retention after visual laser ablation of the prostate [29].
• Among men without an indwelling urethral catheter due to acute urinary retention mean PSA, PSA density and percent free PSA were not significantly different in those with benign and malignant biopsies and/or prostatectomy specimens [30].
• Low-dose naloxone in the treatment of urinary retention during extradural fentanyl causes excessive reversal of analgesia [31].
• This study was performed to establish the validity of intravesical instillation of prostaglandin F2 alpha in the prevention of urinary retention after vaginal surgery [32].

References