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MeSH Review


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Disease relevance of Sterculia


High impact information on Sterculia


Anatomical context of Sterculia

  • In trypsinized, subcultured rabbit aortic smooth muscle cells, Sterculia foetida seed oil extract resulted in an increased incorporation of (3H) thymidine per milligram of protein [7].

Associations of Sterculia with chemical compounds

  • Four refined fibers, cellulose, carboxymethylcellulose gum, locust bean gum, or karaya gum, were added to the basal diet individually for 4 wk each at the level of 0.75 g fiber/100 cal [8].
  • Sterculia foetida oil (50% cyclopropene fatty acids) fed at 0.2% of the diet for three generations and 0.5% fed to first generation rats did not significantly affect breeding [9].
  • Seventeen patients received wheat fiber; 13 were given a laxative regime of sterculia, magnesium sulfate, and mineral oil [10].
  • Cyclopropenoid fatty acids (CPE) isolated from Sterculia foetida oil by urea clathration and reverse phase high performance liquid chromatography (HPLC) were introduced into fungal cultures [11].
  • The absence of rhamnose in human urine following the ingestion of gum karaya (Sterculia) [12].

Gene context of Sterculia

  • Urinary rhamnose estimations following ingestion of gum karaya were requested by the Scientific Committee for Food (EEC) in July 1983 [12].

Analytical, diagnostic and therapeutic context of Sterculia

  • Cyclopropenoids fatty acids (CPFA) from Sterculia striata seed oil were characterized by gas chromatography/mass spectrometry (GC/MS) and quantified by gas chromatography-flame ionization detector (GC-FID) after derivation to fatty acid methyl esters using a cold base-catalyzed procedure [13].


  1. Review article: herbal treatment in gastrointestinal and liver disease--benefits and dangers. Langmead, L., Rampton, D.S. Aliment. Pharmacol. Ther. (2001) [Pubmed]
  2. Salicylic acid in karaya gum patch as a treatment for verruca vulgaris. Bart, B.J., Biglow, J., Vance, J.C., Neveaux, J.L. J. Am. Acad. Dermatol. (1989) [Pubmed]
  3. Carbocyclic fatty acids in plants: biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of Sterculiafoetida. Bao, X., Katz, S., Pollard, M., Ohlrogge, J. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  4. Characterization of cyclopropane fatty-acid synthase from Sterculia foetida. Bao, X., Thelen, J.J., Bonaventure, G., Ohlrogge, J.B. J. Biol. Chem. (2003) [Pubmed]
  5. Dietary fiber: in vitro methods that anticipate nutrition and metabolic activity in humans. Adiotomre, J., Eastwood, M.A., Edwards, C.A., Brydon, W.G. Am. J. Clin. Nutr. (1990) [Pubmed]
  6. The effect of the polysaccharide composition and structure of dietary fibers on cecal fermentation and fecal excretion. Eastwood, M.A., Brydon, W.G., Anderson, D.M. Am. J. Clin. Nutr. (1986) [Pubmed]
  7. The mitogenic effects of methyl sterculate on aortic smooth muscle cells. Leveille, A.S., Fischer-Dzoga, K. Artery (1982) [Pubmed]
  8. Blood lipids and lipoproteins in adult men fed four refined fibers. Behall, K.M., Lee, K.H., Moser, P.B. Am. J. Clin. Nutr. (1984) [Pubmed]
  9. Reproduction and lipid composition of rats fed cyclopropene fatty acids. Nixon, J.E., Eisele, T.A., Hendricks, J.D., Sinnhuber, R.O. J. Nutr. (1977) [Pubmed]
  10. Laxatives after hemorrhoidectomy. Johnson, C.D., Budd, J., Ward, A.J. Dis. Colon Rectum (1987) [Pubmed]
  11. Effects of cyclopropenoid fatty acids on fungal growth and lipid composition. Schmid, K.M., Patterson, G.W. Lipids (1988) [Pubmed]
  12. The absence of rhamnose in human urine following the ingestion of gum karaya (Sterculia). Anderson, A.W., Brydon, W.J., Eastwood, M.A., McDougall, F.J., Anderson, D.M. Food additives and contaminants. (1985) [Pubmed]
  13. Evaluation of a methylation procedure to determine cyclopropenoids fatty acids from Sterculia striata St. Hil. Et Nauds seed oil. Aued-Pimentel, S., Lago, J.H., Chaves, M.H., Kumagai, E.E. Journal of chromatography. A. (2004) [Pubmed]
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