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Chemical Compound Review

STERCULIC ACID     8-(2-octyl-1- cyclopropenyl)octanoic acid

Synonyms: PubChem20404, SureCN31295, CHEBI:9261, AG-G-92884, HSDB 3904, ...
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Disease relevance of C08366


High impact information on C08366


Biological context of C08366


Anatomical context of C08366

  • When liver microsomes prepared from rats fed the control diet were used for the desaturation assays, the presence of free malvalic or sterculic acid in the medium, also highly depressed delta 6- and delta 5-desaturation [7].

Associations of C08366 with other chemical compounds


  1. Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo. Khoo, D.E., Fermor, B., Miller, J., Wood, C.B., Apostolov, K., Barker, W., Williamson, R.C., Habib, N.A. Br. J. Cancer (1991) [Pubmed]
  2. In vitro effects of sterculic acid on lipid biosynthesis in Rhodococcus opacus strain PD630 and isolation of mutants defective in fatty acid desaturation. Wältermann, M., Steinbüchel, A. FEMS Microbiol. Lett. (2000) [Pubmed]
  3. In vivo and in vitro effects of a cyclopropenoid fatty acid on ovine corpus luteum function. Slayden, O., Stormshak, F. Endocrinology (1990) [Pubmed]
  4. Action of a cyclopropenoid fatty acid on the corpus luteum of pregnant and nonpregnant ewes. Tumbelaka, L.I., Slayden, O.V., Stormshak, F. Biol. Reprod. (1994) [Pubmed]
  5. Commentary on F.E. Gomez et al., "Effects of sterculic acid on stearoyl-CoA desaturase in differentiating 3T3-L1 adipocytes". Buist, P.H. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
  6. Effects of sterculic acid on stearoyl-CoA desaturase in differentiating 3T3-L1 adipocytes. Gomez, F.E., Bauman, D.E., Ntambi, J.M., Fox, B.G. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  7. Inhibition of fatty acid delta 6- and delta 5-desaturation by cyclopropene fatty acids in rat liver microsomes. Cao, J., Blond, J.P., Bézard, J. Biochim. Biophys. Acta (1993) [Pubmed]
  8. The mitogenic effects of methyl sterculate on aortic smooth muscle cells. Leveille, A.S., Fischer-Dzoga, K. Artery (1982) [Pubmed]
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