Disease relevance of Gram-Negative Aerobic Bacteria

• The clinical efficacy of ciprofloxacin was evaluated with 21 patients with soft tissue infection due mainly to gram-negative aerobic bacteria [1].
• Aztreonam is selectively active against Gram-negative aerobic bacteria and inactive against Gram-positive bacteria [2].
• The effects of ciprofloxacin, a new quinolone derivative with high activity on gram-negative aerobic bacteria and gram-positive cocci, on haemostasis were investigated in 11 healthy volunteers [3].
• With improved process technology the importance of aerobic bacteria has decreased and the same applies for the Gram negative aerobic bacteria Hafnia protea and Enterobacter cloacae which are capable of surviving beer fermentation [4].

High impact information on Gram-Negative Aerobic Bacteria

• These Gram-negative aerobic bacteria are characterized by an outer membrane that contains glycosphingolipids, but lacks lipopolysaccharide [5].
• U-78608 demonstrated activity primarily against gram-negative aerobic bacteria, with potency generally comparable to that of SQ 83,360 [6].
• Lomefloxacin produced reliable bactericidal activity against gram-negative aerobic bacteria and staphylococci [7].
• Ciprofloxacin should provide serum and soft tissue concentrations above the MICs for most gram-negative aerobic bacteria [1].
• Its resistance to destruction by beta-lactamases results in a broad spectrum of antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria, including many resistant to cephalothin and other cephalosporins [8].

Chemical compound and disease context of Gram-Negative Aerobic Bacteria

• OBJECTIVE: Moxifloxacin is a recently developed fourth-generation methoxyquinolone with a broad spectrum of activity against both Gram-positive and Gram-negative aerobic bacteria and anaerobes [9].
• In contrast, when high levels of nitrate were maintained by periodic replacement of the overlying water with nitrate supplemented anoxic water, the composition of the Achromatium community remained stable over time [10].
• Sch 34343 had good activity (less than 2 mg/l) against most Gram-negative aerobic bacteria whether or not they contained high levels of plasmid-mediated or chromosomally-mediated beta-lactamases [11].
• Studies of the uptake of (14)C-labelled substrates demonstrated that Achromatium cells from freshwater sediments were able to assimilate (14)C from bicarbonate, acetate, and protein hydrolysate; however, (14)C-labelled glucose was not assimilated [12].
• In this study imipenem/cilastatin was used successfully to treat 21 patients with a variety of severe infections caused by Gram-positive and Gram-negative aerobic bacteria [13].

Anatomical context of Gram-Negative Aerobic Bacteria

• Serum, peritoneal fluid, bile, gallbladder wall and pancreatic tissue concentrations of cefotaxime in these groups of pigs exceeded the MIC90 for susceptible species of Gram-negative aerobic bacteria [14].

Gene context of Gram-Negative Aerobic Bacteria

• Gram-negative aerobic bacteria were typed biochemically and analysed for the production of heat-labile and heat-stable enterotoxin [15].

References