Disease relevance of Sphenoid Bone

• We report a case of pituitary adenoma with two compartments, i.e. a part within the sella turcica and a part infiltrating the sphenoid bone beneath the sella, producing growth hormone (GH) and prolactin [1].
• Detection of a sphenoid bone metastasis using Tc-99m MDP bone SPECT of the skull [2].
• There was no previously reported case of postirradiation sarcoma of the sphenoid bone after radiation therapy for nasopharyngeal carcinoma [3].

High impact information on Sphenoid Bone

• Furthermore, higher PTTG expression (P = 0.03) was observed in hormone-secreting tumors that had invaded the sphenoid bone (stages III and IV; 95% CI 3.118-9.715) compared with hormone-secreting tumors that were confined to the pituitary fossa (stages I and II; 95% CI 1.681-3.051) [4].
• Mice homozygous for the disrupted allele (Sim2 -/-) exhibit a cleft of the secondary palate and malformations of the tongue and pterygoid processes of the sphenoid bone [5].
• An example of computer optimization of radiation therapy of a chordoma of the sphenoid bone using x-ray and proton beams is shown and compared with the best plans achieved by an experienced planner [6].
• The tensor veli palatini originated from the scaphoid fossa of the sphenoid bone and the tube [7].
• CASE DESCRIPTION: Two cases of a giant cell tumor involving the sphenoid bone that responded well to chemotherapy using adriamycin after a partial removal of the tumor are presented [8].

Anatomical context of Sphenoid Bone

• In the CLP children, the cranial base width and the bilateral angulation of the sphenoid bone increased [9].
• Thymidine penetrated easily into the sphenoid bone marrow, where it labelled numerous leukocytes [10].

Associations of Sphenoid Bone with chemical compounds

• Those portions of the ring separating the frontal and sphenoid bones (within the orbit and laterally along the coronal suture) show the typical structure of a five-layered suture [11].

Gene context of Sphenoid Bone

• Ocular findings and sphenoid bone morphology in tuberous sclerosis [12].
• In our opinion, this type of craniosynostosis also involves sphenoid bone dysplasia [13].
• Osteogenic sarcoma involving the sphenoid bone is an extremely rare condition [14].

References