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MeSH Review

Sphenoid Bone

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Disease relevance of Sphenoid Bone


High impact information on Sphenoid Bone

  • Furthermore, higher PTTG expression (P = 0.03) was observed in hormone-secreting tumors that had invaded the sphenoid bone (stages III and IV; 95% CI 3.118-9.715) compared with hormone-secreting tumors that were confined to the pituitary fossa (stages I and II; 95% CI 1.681-3.051) [4].
  • Mice homozygous for the disrupted allele (Sim2 -/-) exhibit a cleft of the secondary palate and malformations of the tongue and pterygoid processes of the sphenoid bone [5].
  • An example of computer optimization of radiation therapy of a chordoma of the sphenoid bone using x-ray and proton beams is shown and compared with the best plans achieved by an experienced planner [6].
  • The tensor veli palatini originated from the scaphoid fossa of the sphenoid bone and the tube [7].
  • CASE DESCRIPTION: Two cases of a giant cell tumor involving the sphenoid bone that responded well to chemotherapy using adriamycin after a partial removal of the tumor are presented [8].

Anatomical context of Sphenoid Bone


Associations of Sphenoid Bone with chemical compounds

  • Those portions of the ring separating the frontal and sphenoid bones (within the orbit and laterally along the coronal suture) show the typical structure of a five-layered suture [11].

Gene context of Sphenoid Bone


  1. Pituitary adenoma composed of two compartments each secreting prolactin or growth hormone. Tomono, Y., Nose, T., Maki, Y. Neurosurgery (1987) [Pubmed]
  2. Detection of a sphenoid bone metastasis using Tc-99m MDP bone SPECT of the skull. Ozgen, P., Graves, M.W., Zukerberg, B., Goyal, M., Scheff, A. Clinical nuclear medicine. (1996) [Pubmed]
  3. Postirradiation sarcoma of the sphenoid bone--a case report. Teo, W.Y., Tan, H.K., Goh, B.C., Putti, T.C. Ann. Acad. Med. Singap. (2006) [Pubmed]
  4. Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas. Zhang, X., Horwitz, G.A., Heaney, A.P., Nakashima, M., Prezant, T.R., Bronstein, M.D., Melmed, S. J. Clin. Endocrinol. Metab. (1999) [Pubmed]
  5. Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene. Shamblott, M.J., Bugg, E.M., Lawler, A.M., Gearhart, J.D. Dev. Dyn. (2002) [Pubmed]
  6. Optimization of 3D radiation therapy with both physical and biological end points and constraints. Niemierko, A., Urie, M., Goitein, M. Int. J. Radiat. Oncol. Biol. Phys. (1992) [Pubmed]
  7. A fresh cadaveric study of the paratubal muscles: implications for eustachian tube function in cleft palate. Huang, M.H., Lee, S.T., Rajendran, K. Plast. Reconstr. Surg. (1997) [Pubmed]
  8. Giant cell tumor of the sphenoid bone: long-term follow-up of two cases after chemotherapy. Yamamoto, M., Fukushima, T., Sakamoto, S., Tomonaga, M. Surgical neurology. (1998) [Pubmed]
  9. Cranial base in newborns with complete cleft lip and palate: radiographic study. Mølsted, K., Kjaer, I., Dahl, E. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. (1995) [Pubmed]
  10. Communication of the intracranial space with sphenoid bone marrow in mice. Srebro, Z., Pierścińska, E., Płonkowa, I. Folia biologica. (1993) [Pubmed]
  11. The natural history and pathogenesis of the cranial coronal ring articulations: implications in understanding the pathogenesis of the Crouzon craniostenotic defects. Burdi, A.R., Kusnetz, A.B., Venes, J.L., Gebarski, S.S. The Cleft palate journal. (1986) [Pubmed]
  12. Ocular findings and sphenoid bone morphology in tuberous sclerosis. Russell, B.G., Jensen, H., Kjaer, I. Acta ophthalmologica Scandinavica. Supplement. (1996) [Pubmed]
  13. Surgical treatment of trigonocephaly. Experience with 30 cases. Dhellemmes, P., Pellerin, P., Lejeune, J.P., Lepoutre, F. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. (1986) [Pubmed]
  14. Osteogenic sarcoma of sphenoid bone: an extended lateral skull base approach. Hazarika, P., Nayak, D.R., Sahota, J.S., Rao, D., Kapadia, R.D. The Journal of laryngology and otology. (1995) [Pubmed]
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