High impact information on Eye Enucleation

• We have shown previously that in sSC, eye enucleation reduces NADPH diaphorase staining considerably in all but the most proximal dendrites of nitrergic neurons [1].
• In the rat, monocular eye enucleations on PCD 23 resulted in approximately 55% reduction in the number of PECs in the retinorecipient layers of the contralateral colliculi examined on PCD 44 or PCD 50 [2].
• Selective changes in angiotensin II AT1 and AT2 receptor subtypes in the rat superior colliculus following eye enucleation [3].
• In order to determine the source of the cholinesterase staining in layers 3 and 6 of Galago, we studied, in separate experiments, the effects of kainic acid injections into GL, of eye enucleation, and of lesions of the striate cortex [4].
• Eye enucleations had no effect upon the AChE staining of GL even after a survival period of 3 years [4].

Associations of Eye Enucleation with chemical compounds

• Combination of eye enucleation and visual cortical ablation further decreased the glutamate content in the upper half of the right SGL (29.3%) [5].
• There was no difference in binding in SCN or ME between day and early night, in animals with acute or long-term eye enucleation, or in animals fed a high sucrose diet [6].
• Appearance of substance P-like immunoreactive neurons in the rat superior colliculus after neonatal eye enucleation [7].
• Autoradiography with [11C]MPDX ex vivo demonstrated decreased A1 receptor binding in the superior colliculus of rats deprived of retino-collicular fibers by contralateral eye enucleation [8].
• The patient refused radical surgery including eye enucleation, and received a combination of intravenous caspofungin and voriconazole, along with repeated, conservative, local surgical debridement [9].

Gene context of Eye Enucleation

• Monocular eye enucleations on PCD 23 prevented the expression of calbindin in the medial fifth of the retinorecipient layers of the contralateral SC, while the unilateral removal of the visual cortices had no discernable effect on the numbers and distribution of the CECs in either SC [10].
• These findings together with the demonstration that bilateral eye enucleation does not decrease the number of SP-immunoreactive nerve fibres in the SCN indicate that SP is not a neurotransmitter in the RHT but could be an intrinsic neurotransmitter of the SCN modulating photic input to the clock [11].
• We conclude that disruption to the visual system caused by eye enucleation or strabismus is not equivalent [12].
• The dense plexus of calretinin-positive fibers in the superficial layers of the colliculus was completely eliminated after eye enucleation [13].

References