Chemical Compound Review:
FAD-104 7-[2-[(2R,4S)-4- [(2S,3R,4R,5S,6S)-3-fluoro...
Synonyms:
AC1L3GZW, LS-74323, ME2303, ME 2303, 116521-53-0
- A fluorine-containing anthracycline (ME2303) as a new antitumor agent against murine and human tumors and their multidrug-resistant sublines. Tsuruo, T., Yusa, K., Sudo, Y., Takamori, R., Sugimoto, Y. Cancer Res. (1989)
- Differential intracellular processing of the anthracycline drug ME2303 in doxorubicin-sensitive (A2780) and -resistant (A2780AD) human ovarian cancer cells as studied with confocal laser scanning microscopy and image analysis. Huxham, I.M., Barlow, A.L., Lewis, A.D., Plumb, J., Mairs, R.J., Gaze, M.N., Workman, P. Int. J. Cancer (1994)
- Effects of antitumor agents on subcutaneous implants and hepatic metastases of colon carcinoma 26 in mice. Iigo, M., Nishikata, K., Nakajima, Y., Araki, E. Jpn. J. Cancer Res. (1992)
- Antitumor activity of ME2303, a fluorine-containing anthracycline, against human tumors implanted in nude mice. Tsuruo, T., Sato, S., Yusa, K. Jpn. J. Cancer Res. (1989)
- Comparison of antitumor activity of new anthracycline analogues, ME2303, KRN8602, and SM5887 using human lung cancer cell lines. Takigawa, N., Ohnoshi, T., Ueoka, H., Kiura, K., Kimura, I. Acta Med. Okayama (1992)
- Biological properties of ME2303 (FAD-104), a new anthracycline. Omoto, S., Kondo, S., Fukatsu, S., Takeuchi, T., Umezawa, K., Tsuchiya, T., Umezawa, S. Drugs under experimental and clinical research. (1988)
- Comparison of pharmacokinetics of M1, M2, M3, and M4 after intravenous administration of DA-125 or ME2303 to mice and rats. New adriamycin analogues containing fluorine. Yoon, E.J., Lee, W.I., Shim, H.J., Lee, S.D., Kim, W.B., Yang, J., Lee, M.G. Biopharmaceutics & drug disposition. (1996)
- Therapeutic activity and tissue distribution of ME2303, a new anthracycline containing fluorine, and its metabolites in mice bearing hepatic metastases of Lewis lung carcinoma. Iigo, M., Nishikata, K., Nakajima, Y., Hoshi, A., Kadosawa, H., Nakajima, S. Anticancer Drugs (1990)
- Effects of fluoro-doxorubicin (ME2303) on microtubules: influence of different classes of microtubule-associated proteins. Fromes, Y., Gounon, P., Tapiero, H., Fellous, A. J. Protein Chem. (1996)
- Evaluation of novel platinum complexes, inhibitors of topoisomerase I and II in non-small cell lung cancer (NSCLC) sublines resistant to cisplatin. Fukuda, M., Ohe, Y., Kanzawa, F., Oka, M., Hara, K., Saijo, N. Anticancer Res. (1995)