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Chemical Compound Review

Fluorkill     2-fluoroethanamide

Synonyms: Megatox, Fussol, Navron, Yanock, Baran, ...
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Disease relevance of Fussol


High impact information on Fussol


Biological context of Fussol


Anatomical context of Fussol


Associations of Fussol with other chemical compounds


Gene context of Fussol

  • Seven fluoroacetamide-resistant mutants with low amidase activity gave rise to secondary mutant strains on succinate+butyramide plates [11].
  • Among mutants of Pseudomonas aeruginosa isolated from fluoroacetamide medium were some which synthesized amidase at about 5% of the rate of the parent constitutive strain, PAC101 [11].

Analytical, diagnostic and therapeutic context of Fussol

  • The isolated metabolites were derivatized with N-methyl-N-trimethylsilyltri- fluoroacetamide/trimethyliodosilane and analysed by gas chromatography/mass spectrometry with electron impact (EI) ionization at 70 eV [12].


  1. Insertion and replication of the Pseudomonas aeruginosa mutator phage D3112. Rehmat, S., Shapiro, J.A. Mol. Gen. Genet. (1983) [Pubmed]
  2. Isolation and phenotypic characterization of Pseudomonas aeruginosa pseudorevertants containing suppressors of the catabolite repression control-defective crc-10 allele. Collier, D.N., Spence, C., Cox, M.J., Phibbs, P.V. FEMS Microbiol. Lett. (2001) [Pubmed]
  3. Acute inhalation toxicity study of 2-fluoroacetamide in rats. Singh, M., Vijayaraghavan, R., Pant, S.C., Sugendran, K., Kumar, P., Singh, R., Purnanand, n.u.l.l. Biomed. Environ. Sci. (2000) [Pubmed]
  4. Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids. Tong, Z., Board, P.G., Anders, M.W. Chem. Res. Toxicol. (1998) [Pubmed]
  5. Deletion of the trichodiene synthase gene of Fusarium venenatum: two systems for repeated gene deletions. Royer, J.C., Christianson, L.M., Yoder, W.T., Gambetta, G.A., Klotz, A.V., Morris, C.L., Brody, H., Otani, S. Fungal Genet. Biol. (1999) [Pubmed]
  6. Genetic analysis of amdS transformants of Aspergillus niger and their use in chromosome mapping. Debets, A.J., Swart, K., Holub, E.F., Goosen, T., Bos, C.J. Mol. Gen. Genet. (1990) [Pubmed]
  7. Experiments on direct and secondary poisoning by fluoroacetamide (1081) in wildlife and domestic carnivores. Braverman, Y. J. Wildl. Dis. (1979) [Pubmed]
  8. Fast detection of fluoroacetamide in body fluid using gas chromatography-mass spectrometry after solid-phase microextraction. Cai, X., Zhang, D., Ju, H., Wu, G., Liu, X. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2004) [Pubmed]
  9. The recovery and identification of fluoroacetamide and fluoroacetic acid from tissues. Stevens, H.M., Moffat, A.C., Drayton, J.V. Forensic science. (1976) [Pubmed]
  10. Isolation of amidase-negative mutants of Pseudomonas aeruginosa using glycollamide as a selective agent. Brown, P.R., Tata, R. J. Gen. Microbiol. (1987) [Pubmed]
  11. Catabolite repression of Pseudomonas aeruginosa amidase: isolation of promotor mutants. Smyth, P.F., Clarke, P.H. J. Gen. Microbiol. (1975) [Pubmed]
  12. Metabolism of boldenone in man: gas chromatographic/mass spectrometric identification of urinary excreted metabolites and determination of excretion rates. Schänzer, W., Donike, M. Biol. Mass Spectrom. (1992) [Pubmed]
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