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Chemical Compound Review:

ChS-RR2 2-[4-(oxiran-2- ylmethoxy)butoxymethyl]oxirane

Synonyms: CCRIS 2639, Araldit DY 026, HSDB 5459, NSC-24834, LS-1040, ...

Gomez, C.G. et al., Subramanian, A. et al., Diogo, M.M. et al., Jappe, U. et al., Tomaz, C.T. et al., et al.

Subramanian, Lin,

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Disease relevance of ChS-RR2

This work presents studies on the interactions of supercoiled plasmid DNA and Escherichia coli genomic DNA (gDNA) and RNA, with an hydrophobic interaction chromatography (HIC) gel, obtained by derivatisation of Sepharose CL-6B with 1,4-butanediol diglycidyl ether [1].

High impact information on ChS-RR2

The kinetics of 1,4-butanediol diglycidyl ether crosslinking of dermal sheep collagen [2].
Patch tests showed positive reactions at day 3 to nickel sulfate, epoxy resin based on diglycidyl ether of bisphenol F (DGEBF) and 1,4-butanediol diglycidyl ether (1,4-BDDGE) [3].
These products were submitted to chemical modifications using 1,4-butanediol diglycidyl ether (BDGE) in activation reactions and different chelating agents (iminodiacetic acid, IDA; disodium ethylenediamine tetraacetate, EDTA; and hexamethylenediamine tetrapropanoic acid, HMDTP) in coupling reactions to attain Fe(3+)-containing sorbents [4].
In the present study, chitosan substrates are crosslinked with a functional diepoxide (1,4 butanediol diglycidyl ether) to alter its mechanical property, and the viability and proliferation of the canine articular chondrocytes seeded on the crosslinked surface are further assayed [5].

Analytical, diagnostic and therapeutic context of ChS-RR2

The concentrated enzyme solution was then fractionated on Sepharose CL-6B modified by covalent immobilization of 1,4-butanediol diglycidyl ether [6].

References

Studies on the retention of plasmid DNA and Escherichia coli nucleic acids by hydrophobic interaction chromatography. Diogo, M.M., Queiroz, J.A., Prazeres, D.M. Bioseparation (2001) [Pubmed]
The kinetics of 1,4-butanediol diglycidyl ether crosslinking of dermal sheep collagen. Zeeman, R., Dijkstra, P.J., van Wachem, P.B., van Luyn, M.J., Hendriks, M., Cahalan, P.T., Feijen, J. J. Biomed. Mater. Res. (2000) [Pubmed]
Contact vitiligo following a strong patch test reaction to triglycidyl-p-aminophenol in an aircraft industry worker: case report and review of the literature. Jappe, U., Geier, J., Hausen, B.M. Contact Derm. (2005) [Pubmed]
Influence of the morphology of poly(EGDMA-co-HEMA) on the chemical modifications and retention of O-phosphothreonine. Gomez, C.G., Alvarez, C.I., Strumia, M.C. J. Biochem. Biophys. Methods (2003) [Pubmed]
Crosslinked chitosan: its physical properties and the effects of matrix stiffness on chondrocyte cell morphology and proliferation. Subramanian, A., Lin, H.Y. Journal of biomedical materials research. Part A. (2005) [Pubmed]
Studies on the chromatographic fractionation of Trichoderma reesei cellulases by hydrophobic interaction. Tomaz, C.T., Queiroz, J.A. Journal of chromatography. A. (1999) [Pubmed]

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