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Chemical Compound Review

t-Butylquinone     2-tert-butylcyclohexa-2,5- diene-1,4-dione

Synonyms: PubChem14593, SureCN49453, ACMC-1CJP1, CCRIS 1263, AG-F-25334, ...
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Disease relevance of tert-Butyl-p-quinone


High impact information on tert-Butyl-p-quinone


Biological context of tert-Butyl-p-quinone


Anatomical context of tert-Butyl-p-quinone


Associations of tert-Butyl-p-quinone with other chemical compounds


Gene context of tert-Butyl-p-quinone


  1. Mutagenicity of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites in short-term tests in vitro. Matsuoka, A., Matsui, M., Miyata, N., Sofuni, T., Ishidate, M. Mutat. Res. (1990) [Pubmed]
  2. Metabolism of 3-tert-butyl-4-hydroxyanisole by microsomal fractions and isolated rat hepatocytes. Cummings, S.W., Ansari, G.A., Guengerich, F.P., Crouch, L.S., Prough, R.A. Cancer Res. (1985) [Pubmed]
  3. DNA damage in forestomach epithelium from male F344 rats following oral administration of tert-butylquinone, one of the forestomach metabolites of 3-BHA. Morimoto, K., Tsuji, K., Iio, T., Miyata, N., Uchida, A., Osawa, R., Kitsutaka, H., Takahashi, A. Carcinogenesis (1991) [Pubmed]
  4. Inhibition of hepatic microsomal cytochrome P-450 dependent monooxygenation activity by the antioxidant 3-tert-butyl-4-hydroxyanisole. Rodrigues, A.D., Fernandez, D., Nosarzewski, M.A., Pierce, W.M., Prough, R.A. Chem. Res. Toxicol. (1991) [Pubmed]
  5. Tyrosinase-mediated formation of a reactive quinone from the depigmenting agents, 4-tert-butylphenol and 4-tert-butylcatechol. Thörneby-Andersson, K., Sterner, O., Hansson, C. Pigment Cell Res. (2000) [Pubmed]
  6. On the mechanisms of 3-tert-butyl-4-hydroxyanisole- and its metabolites-induced cytotoxicities in isolated rat hepatocytes. Nakagawa, Y., Nakajima, K., Moore, G., Moldéus, P. Eur. J. Pharmacol. (1994) [Pubmed]
  7. The effect of the tert-butylquinone metabolite of butylated hydroxyanisole on cytochrome P-450 monooxygenase activity. Cummings, S.W., Curtis, B.B., Peterson, J.A., Prough, R.A. Xenobiotica (1990) [Pubmed]
  8. Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole. Kahl, R., Weinke, S., Kappus, H. Toxicology (1989) [Pubmed]
  9. Cell death induced by the phenolic antioxidant tert-butylhydroquinone and its metabolite tert-butylquinone in human monocytic leukemia U937 cells. Okubo, T., Yokoyama, Y., Kano, K., Kano, I. Food Chem. Toxicol. (2003) [Pubmed]
  10. Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide. Tajima, K., Hashizaki, M., Yamamoto, K., Mizutani, T. Drug Metab. Dispos. (1992) [Pubmed]
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