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Chemical Compound Review

Bronocot     2-bromo-2-nitro-propane-1,3- diol

Synonyms: Bronosol, Bronotak, bronopol, Bronidiol, Bronopolu, ...
 
 
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Disease relevance of Bronotak

 

High impact information on Bronotak

 

Chemical compound and disease context of Bronotak

 

Biological context of Bronotak

 

Analytical, diagnostic and therapeutic context of Bronotak

  • In addition, the parameters for the HPLC analysis of bronopol were optimised [15].
  • In only 17 cases (0.21%) was the patch test reaction to Bronopol considered to be of current or past clinical relevance [16].
  • The sensitivity of the method towards bronopol degradation in aqueous solution is comparable to that obtained by gas-liquid chromatography and enzymatic assays described elsewhere [7].
  • A simple and sensitive detection of bronopol and bromonitroethanol (down to 2 micrograms) on a silica gel 60 F254 precoated thin layer chromatography plate based on the formation of the chromophoric derivative in the presence of ammonia vapour has been described [7].
  • A study on the stability of bronopol in bronopol lotion by ion-paired reversed-phase high performance liquid chromatography [17].

References

  1. Antibacterial action of 2-bromo-2-nitropropane-1,3-diol (bronopol). Shepherd, J.A., Waigh, R.D., Gilbert, P. Antimicrob. Agents Chemother. (1988) [Pubmed]
  2. Allergic contact dermatitis to 2-bromo-2-nitropropane-1,3-diol in a hydrophilic ointment. Storrs, F.J., Bell, D.E. J. Am. Acad. Dermatol. (1983) [Pubmed]
  3. Contact dermatitis due to Bronopol. Camarasa, J.G. Contact Derm. (1986) [Pubmed]
  4. Hygiene in the prevention of udder infections. VI. Comparative efficacy of a teat dip under experimental and natural exposure to mastitis pathogens. Philpot, W.N., Pankey, J.W., Boddie, R.L. J. Dairy Sci. (1978) [Pubmed]
  5. Plasma surface modification of poly vinyl chloride for improvement of antibacterial properties. Zhang, W., Chu, P.K., Ji, J., Zhang, Y., Liu, X., Fu, R.K., Ha, P.C., Yan, Q. Biomaterials (2006) [Pubmed]
  6. Reduction of mastitis caused by experimental challenge with Staphylococcus aureus and Streptococcus agalactiae by use of a quaternary ammonium and halogen-mixture teat dip. Boddie, R.L., Nickerson, S.C. J. Dairy Sci. (2002) [Pubmed]
  7. Rapid ultraviolet spectrophotometric determination of bronopol: application to raw material analysis and kinetic studies of bronopol degradation. Sanyal, A.K., Basu, M., Banerjee, A.B. Journal of pharmaceutical and biomedical analysis. (1996) [Pubmed]
  8. Reactions to Quaternium 15, Bronopol and Germall 115 in a standard series. Ford, G.P., Beck, M.H. Contact Derm. (1986) [Pubmed]
  9. Bronopol allergic contact dermatitis. Peters, M.S., Connolly, S.M., Schroeter, A.L. Contact Derm. (1983) [Pubmed]
  10. Occupational allergic contact dermatitis from both 2-bromo-2-nitropropane-1,3-diol and methylchloroisothiazolinone plus methylisothiazolinone in spin finish. Podmore, P. Contact Derm. (2000) [Pubmed]
  11. Potassium fluxes on hyperosmotic shock and the effect of phenol and bronopol (2-bromo-2-nitropropan-1,3-diol) on deplasmolysis of Pseudomonas aeruginosa. Kroll, R.G., Anagnostopoulos, G.D. J. Appl. Bacteriol. (1981) [Pubmed]
  12. The biotransformation and disposition of bronopol following topical and intravenous administration to rats. Buttar, H.S., Downie, R.H. Toxicol. Lett. (1980) [Pubmed]
  13. The percutaneous absorption and disposition of the antibacterial agent bronopol in rats and rabbits. Risdall, P.C., Risdall, P.C., Moore, D.H., Chasselaud, L.F. Food and cosmetics toxicology. (1976) [Pubmed]
  14. N-nitrosoalkanolamines in cosmetics. Eisenbrand, G., Blankart, M., Sommer, H., Weber, B. IARC Sci. Publ. (1991) [Pubmed]
  15. Determination of bronopol and its degradation products by HPLC. Wang, H., Provan, G.J., Helliwell, K. Journal of pharmaceutical and biomedical analysis. (2002) [Pubmed]
  16. Contact allergy to Bronopol. Frosch, P.J., White, I.R., Rycroft, R.J., Lahti, A., Burrows, D., Camarasa, J.G., Ducombs, G., Wilkinson, J.D. Contact Derm. (1990) [Pubmed]
  17. A study on the stability of bronopol in bronopol lotion by ion-paired reversed-phase high performance liquid chromatography. Lian, H.Z., Zhang, W.B., Miao, J., Jiang, Q., Mao, L., Zong, L., Li, L., Wu, X.X., Cheng, R.M. Journal of pharmaceutical and biomedical analysis. (1997) [Pubmed]
 
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