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Disease relevance of Lubrication


High impact information on Lubrication

  • Alkylimidazolium tetrafluoroborates are promising versatile lubricants for the contact of steel/steel, steel/aluminium, steel/copper, steel/SiO2, Si3N4/SiO2, steel/Si(100), steel/sialon ceramics and Si3N4/sialon ceramics; they show excellent friction reduction, antiwear performance and high load-carrying capacity [5].
  • BACKGROUND: Chlorhexidine is a disinfectant that has been used in skin and mouth washes and as a preservative in some vaginal lubricants [6].
  • Despite the absence of efficacy or safety data, many gay men use sexual lubricants containing nonoxynol-9 (N-9), a detergent-based spermicide under evaluation for efficacy as a vaginal microbicide [7].
  • Comparison of a microbicidal povidone-iodine gel and a placebo gel as catheter lubricants [8].
  • The major components of plastic extracts were even-carbon-chain n-alkanes (C16-C40), the plasticizer di-2-ethylhexyl phthalate, and the antioxidants and lubricants/antiadhesives Irganox 1076, Irgafos 168, and its oxidation product tris(2,4-di-tertbutylphenyl) phosphate [9].

Chemical compound and disease context of Lubrication


Biological context of Lubrication


Anatomical context of Lubrication


Associations of Lubrication with chemical compounds


Gene context of Lubrication

  • The other conventional lubricants such as magnesium stearate (MGST), stearic acid (STAC), and glyceryl behenate (COMP) were also tested along with HBN [23].
  • The optimised biodegradability test system "O2/CO2 Headspace Test with GC-TCD" is used for the assessment of synthetic ester lubricants [24].
  • On a molar basis, the best lubricants of the purified salivary molecules were MG1 greater than MG2 approximately nonglycosylated alpha-amylases approximately glycosylated alpha-amylases [25].
  • Using these components, OTC sexual lubricants could be reformulated to optimize their anti-HIV activity [4].
  • Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions [26].

Analytical, diagnostic and therapeutic context of Lubrication


  1. Vaginal absorption of hexachlorophene during labor. Strickland, D.M., Leonard, R.G., Stavchansky, S., Benoit, T., Wilson, R.T. Am. J. Obstet. Gynecol. (1983) [Pubmed]
  2. The effect of vaginal lubricants on sperm motility in vitro. Goldenberg, R.L., White, R. Fertil. Steril. (1975) [Pubmed]
  3. Lea's Shield: a phase I postcoital study of a new contraceptive barrier device. Archer, D.F., Mauck, C.K., Viniegra-Sibal, A., Anderson, F.D. Contraception. (1995) [Pubmed]
  4. Preventing sexual transmission of HIV: anti-HIV bioregulatory and homeostatic components of commercial sexual lubricants. Nguyen, D., Lee, H., Poast, J., Cloyd, M.W., Baron, S. J. Biol. Regul. Homeost. Agents (2004) [Pubmed]
  5. Room-temperature ionic liquids: a novel versatile lubricant. Ye, C., Liu, W., Chen, Y., Yu, L. Chem. Commun. (Camb.) (2001) [Pubmed]
  6. Effect of chlorhexidine on genital microflora, Neisseria gonorrhoeae, and Trichomonas vaginalis in vitro. Rabe, L.K., Hillier, S.L. Sexually transmitted diseases. (2000) [Pubmed]
  7. Rectal microbicides for U.S. gay men. Are clinical trials needed? Are they feasible? HIVNET Vaccine Preparedness Study Protocol Team. Gross, M., Buchbinder, S.P., Celum, C., Heagerty, P., Seage, G.R. Sexually transmitted diseases. (1998) [Pubmed]
  8. Comparison of a microbicidal povidone-iodine gel and a placebo gel as catheter lubricants. Harrison, L.H. J. Urol. (1980) [Pubmed]
  9. Combustion products of plastics as indicators for refuse burning in the atmosphere. Simoneit, B.R., Medeiros, P.M., Didyk, B.M. Environ. Sci. Technol. (2005) [Pubmed]
  10. Acute toxicity investigations of ester-based lubricants by using biotests with algae and bacteria. Michel, K., Brinkmann, C., Hahn, S., Dott, W., Eisentraeger, A. Environ. Toxicol. (2004) [Pubmed]
  11. Vaginal lubricants: effect of glycerin and egg white on sperm motility and progression in vitro. Tulandi, T., McInnes, R.A. Fertil. Steril. (1984) [Pubmed]
  12. Glycerin fatty acid esters as a new lubricant of tablets. Aoshima, H., Miyagisnima, A., Nozawa, Y., Sadzuka, Y., Sonobe, T. International journal of pharmaceutics. (2005) [Pubmed]
  13. Effects of toluidine blue and destaining reagents used in sexual assault examinations on the ability to obtain DNA profiles from postcoital vaginal swabs. Hochmeister, M.N., Whelan, M., Borer, U.V., Gehrig, C., Binda, S., Berzlanovich, A., Rauch, E., Dirnhofer, R. J. Forensic Sci. (1997) [Pubmed]
  14. New lubricants from vegetable oil: cyclic acetals of methyl 9,10-dihydroxystearate. Filley, J. Bioresour. Technol. (2005) [Pubmed]
  15. Electrical impedance of the cochlear implant lubricants hyaluronic acid, oxycellulose, and glycerin. Mens, L.H., Oostendorp, T.F., Hombergen, G.C., den Broek, P. The Annals of otology, rhinology, and laryngology. (1997) [Pubmed]
  16. Preservative-free artificial tear preparations. Assessment of corneal epithelial toxic effects. Berdy, G.J., Abelson, M.B., Smith, L.M., George, M.A. Arch. Ophthalmol. (1992) [Pubmed]
  17. Static forces, structure and flow properties of complex fluids in highly confined geometries. Benz, M., Chen, N., Jay, G., Israelachvili, J. Annals of biomedical engineering. (2005) [Pubmed]
  18. Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution. Chowhan, Z.T., Chi, L.H. Journal of pharmaceutical sciences. (1986) [Pubmed]
  19. Intrinsic adhesion force of lubricants to steel surface. Lee, J. Journal of pharmaceutical sciences. (2004) [Pubmed]
  20. Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. Matsuda, Y., Minamida, Y., Hayashi, S.I. Journal of pharmaceutical sciences. (1976) [Pubmed]
  21. Pathogenesis of cholesteryl lipidosis of adrenocortical and ovarian interstitial cells in F344 rats caused by tricresyl phosphate and butylated triphenyl phosphate. Latendresse, J.R., Azhar, S., Brooks, C.L., Capen, C.C. Toxicol. Appl. Pharmacol. (1993) [Pubmed]
  22. Wear simulation of UHMWPE for total hip replacement with a multidirectional motion pin-on-disk device: effects of counterface material, contact area, and lubricant. Saikko, V., Ahlroos, T. J. Biomed. Mater. Res. (2000) [Pubmed]
  23. Evaluation of hexagonal boron nitride as a new tablet lubricant. Turkoglu, M., Sahin, I., San, T. Pharmaceutical development and technology. (2005) [Pubmed]
  24. Biodegradability testing of synthetic ester lubricants--effects of additives and usage. Eisentraeger, A., Schmidt, M., Murrenhoff, H., Dott, W., Hahn, S. Chemosphere (2002) [Pubmed]
  25. Lubrication of selected salivary molecules and artificial salivas. Aguirre, A., Mendoza, B., Reddy, M.S., Scannapieco, F.A., Levine, M.J., Hatton, M.N. Dysphagia. (1989) [Pubmed]
  26. Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. Asker, A.F., Saied, K.M., Abdel-Khalek, M.M. Die Pharmazie. (1975) [Pubmed]
  27. An in vitro study of biological safety of condoms and their additives. Motsoane, N.A., Bester, M.J., Pretorius, E., Becker, P.J. Human & experimental toxicology. (2003) [Pubmed]
  28. Comparison of topical anesthetics and lubricants prior to urethral catheterization in males: a randomized controlled trial. Siderias, J., Guadio, F., Singer, A.J. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. (2004) [Pubmed]
  29. Effect of lubricant type and concentration on the punch tip adherence of model ibuprofen formulations. Roberts, M., Ford, J.L., MacLeod, G.S., Fell, J.T., Smith, G.W., Rowe, P.H., Dyas, A.M. J. Pharm. Pharmacol. (2004) [Pubmed]
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