The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

FCdR     4-amino-5-fluoro-1-[(2R,5R)- 4-hydroxy-5...

Synonyms: SureCN207023, LS-372, NSC 48006, BRN 0619209, AC1L18MM, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Fluorodeoxycytidine


High impact information on Fluorodeoxycytidine


Biological context of Fluorodeoxycytidine


Anatomical context of Fluorodeoxycytidine


Associations of Fluorodeoxycytidine with other chemical compounds


Gene context of Fluorodeoxycytidine


  1. Tumor-selective metabolism of 5-fluoro-2'-deoxycytidine coadministered with tetrahydrouridine compared to 5-fluorouracil in mice bearing Lewis lung carcinoma. Boothman, D.A., Briggle, T.V., Greer, S. Cancer Res. (1987) [Pubmed]
  2. Sequence-specific and mechanism-based crosslinking of Dcm DNA cytosine-C5 methyltransferase of E. coli K-12 to synthetic oligonucleotides containing 5-fluoro-2'-deoxycytidine. Hanck, T., Schmidt, S., Fritz, H.J. Nucleic Acids Res. (1993) [Pubmed]
  3. Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation. Greer, S., Schwade, J., Marion, H.S. Int. J. Radiat. Oncol. Biol. Phys. (1995) [Pubmed]
  4. Thymidylate synthetase inhibitors and fragile site expression in lymphocytes. Jacky, P.B., Sutherland, G.R. Am. J. Hum. Genet. (1983) [Pubmed]
  5. Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies. Mekras, J.A., Boothman, D.A., Perez, L.M., Greer, S. Cancer Res. (1984) [Pubmed]
  6. Utilization of 5-fluoro-2'-deoxyuridine triphosphate and 5-fluoro-2'-deoxycytidine triphosphate in DNA synthesis by DNA polymerases alpha and beta from calf thymus. Tanaka, M., Yoshida, S., Saneyoshi, M., Yamaguchi, T. Cancer Res. (1981) [Pubmed]
  7. Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice. Beumer, J.H., Eiseman, J.L., Parise, R.A., Joseph, E., Holleran, J.L., Covey, J.M., Egorin, M.J. Clin. Cancer Res. (2006) [Pubmed]
  8. Metabolic channeling of 5-fluoro-2'-deoxycytidine utilizing inhibitors of its deamination in cell culture. Boothman, D.A., Briggle, T.V., Greer, S. Mol. Pharmacol. (1985) [Pubmed]
  9. Induction of sister chromatid exchanges by 5-fluorodeoxycytidine: correlation with DNA methylation. Chambers, J.C., Taylor, J.H. Chromosoma (1982) [Pubmed]
  10. Correlation of vertebral malformations with the synthesis and content of mucopolysaccharides during chondrogenesis. Kleinebrecht, J., Svejcar, J. Virchows Archiv. A, Pathological anatomy and histology. (1979) [Pubmed]
  11. Monitoring gene therapy with herpes simplex virus thymidine kinase in hepatoma cells: uptake of specific substrates. Haberkorn, U., Altmann, A., Morr, I., Knopf, K.W., Germann, C., Haeckel, R., Oberdorfer, F., van Kaick, G. J. Nucl. Med. (1997) [Pubmed]
  12. Micronuclei induced by modulators of methylation: analogs of 5-azacytidine. Stopper, H., Körber, C., Gibis, P., Spencer, D.L., Caspary, W.J. Carcinogenesis (1995) [Pubmed]
  13. Five-chlorodeoxycytidine, a tumor-selective enzyme-driven radiosensitizer, effectively controls five advanced human tumors in nude mice. Greer, S., Alvarez, M., Mas, M., Wozniak, C., Arnold, D., Knapinska, A., Norris, C., Burk, R., Aller, A., Dauphinée, M. Int. J. Radiat. Oncol. Biol. Phys. (2001) [Pubmed]
  14. 5-Fluoro-2'-deoxycytidine 5'-monophosphate is a mechanism-based inhibitor of thymidylate synthase. Liu, L., Santi, D.V. Biochim. Biophys. Acta (1994) [Pubmed]
WikiGenes - Universities