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Chemical Compound Review

AG-K-73604     4-oxohex-2-enedioic acid

Synonyms: CTK7I5345, AC1L196V, 24740-88-3, maleylacetic acid, Maleoylacetic acid, ...
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Disease relevance of CPD-294


High impact information on CPD-294


Chemical compound and disease context of CPD-294


Biological context of CPD-294


Associations of CPD-294 with other chemical compounds

  • The clcD structural gene encodes dienelactone hydrolase (EC, an enzyme that catalyzes the conversion of dienelactones to maleylacetate [15].

Gene context of CPD-294


Analytical, diagnostic and therapeutic context of CPD-294


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  2. A novel p-nitrophenol degradation gene cluster from a gram-positive bacterium, Rhodococcus opacus SAO101. Kitagawa, W., Kimura, N., Kamagata, Y. J. Bacteriol. (2004) [Pubmed]
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  4. Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100. Zaborina, O., Daubaras, D.L., Zago, A., Xun, L., Saido, K., Klem, T., Nikolic, D., Chakrabarty, A.M. J. Bacteriol. (1998) [Pubmed]
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  6. Genetic Characterization of the Resorcinol Catabolic Pathway in Corynebacterium glutamicum. Huang, Y., Zhao, K.X., Shen, X.H., Chaudhry, M.T., Jiang, C.Y., Liu, S.J. Appl. Environ. Microbiol. (2006) [Pubmed]
  7. Identification and characterization of genes involved in the downstream degradation pathway of gamma-hexachlorocyclohexane in Sphingomonas paucimobilis UT26. Endo, R., Kamakura, M., Miyauchi, K., Fukuda, M., Ohtsubo, Y., Tsuda, M., Nagata, Y. J. Bacteriol. (2005) [Pubmed]
  8. New bacterial pathway for 4- and 5-chlorosalicylate degradation via 4-chlorocatechol and maleylacetate in Pseudomonas sp. strain MT1. Nikodem, P., Hecht, V., Schlömann, M., Pieper, D.H. J. Bacteriol. (2003) [Pubmed]
  9. Organization and regulation of pentachlorophenol-degrading genes in Sphingobium chlorophenolicum ATCC 39723. Cai, M., Xun, L. J. Bacteriol. (2002) [Pubmed]
  10. Cloning and sequencing of a novel meta-cleavage dioxygenase gene whose product is involved in degradation of gamma-hexachlorocyclohexane in Sphingomonas paucimobilis. Miyauchi, K., Adachi, Y., Nagata, Y., Takagi, M. J. Bacteriol. (1999) [Pubmed]
  11. Maleylacetate reductase of Pseudomonas sp. strain B13: dechlorination of chloromaleylacetates, metabolites in the degradation of chloroaromatic compounds. Kaschabek, S.R., Reineke, W. Arch. Microbiol. (1992) [Pubmed]
  12. Catalysis by dienelactone hydrolase: a variation on the protease mechanism. Cheah, E., Ashley, G.W., Gary, J., Ollis, D. Proteins (1993) [Pubmed]
  13. Evidence that operons tcb, tfd, and clc encode maleylacetate reductase, the fourth enzyme of the modified ortho pathway. Kasberg, T., Daubaras, D.L., Chakrabarty, A.M., Kinzelt, D., Reineke, W. J. Bacteriol. (1995) [Pubmed]
  14. Recruitment of a chromosomally encoded maleylacetate reductase for degradation of 2,4-dichlorophenoxyacetic acid by plasmid pJP4. Kukor, J.J., Olsen, R.H., Siak, J.S. J. Bacteriol. (1989) [Pubmed]
  15. Nucleotide sequence and expression of clcD, a plasmid-borne dienelactone hydrolase gene from Pseudomonas sp. strain B13. Frantz, B., Ngai, K.L., Chatterjee, D.K., Ornston, L.N., Chakrabarty, A.M. J. Bacteriol. (1987) [Pubmed]
  16. Purification and characterization of maleylacetate reductase from Nocardioides simplex 3E utilizing phenoxyalcanoic herbicides 2,4-D and 2,4,5-T. Travkin, V.M., Linko, E.V., Golovleva, L.A. Biochemistry Mosc. (1999) [Pubmed]
  17. Cloning, characterization, and sequence analysis of the clcE gene encoding the maleylacetate reductase of Pseudomonas sp. strain B13. Kasberg, T., Seibert, V., Schlömann, M., Reineke, W. J. Bacteriol. (1997) [Pubmed]
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