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Chemical Compound Review

vesamicol     2-(4-phenyl-1- piperidyl)cyclohexan-1-ol

Synonyms: CHEMBL20943, AGN-PC-00YT7C, SureCN571598, AG-J-88370, BSPBio_003302, ...
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High impact information on vesamicol


Biological context of vesamicol


Anatomical context of vesamicol


Associations of vesamicol with other chemical compounds


  1. Is an acetylcholine transport system responsible for nonquantal release of acetylcholine at the rodent myoneural junction? Edwards, C., Dolezal, V., Tucek, S., Zemková, H., Vyskocil, F. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  2. N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. Efange, S.M., Kamath, A.P., Khare, A.B., Kung, M.P., Mach, R.H., Parsons, S.M. J. Med. Chem. (1997) [Pubmed]
  3. Mobilization of a vesamicol-insensitive pool of acetylcholine from a sympathetic ganglion by ouabain. Prado, M.A., Gomez, M.V., Collier, B. J. Neurochem. (1993) [Pubmed]
  4. Acetylcholine mobilization in a sympathetic ganglion in the presence and absence of 2-(4-phenylpiperidino)cyclohexanol (AH5183). Cabeza, R., Collier, B. J. Neurochem. (1988) [Pubmed]
  5. Effect of 2-(4-phenylpiperidino)cyclohexanol on acetylcholine release and subcellular distribution in rat striatal slices. Rícný, J., Collier, B. J. Neurochem. (1986) [Pubmed]
  6. Vesamicol analogues as sigma ligands. Molecular determinants of selectivity at the vesamicol receptor. Efange, S.M., Mach, R.H., Smith, C.R., Khare, A.B., Foulon, C., Akella, S.K., Childers, S.R., Parsons, S.M. Biochem. Pharmacol. (1995) [Pubmed]
  7. Effects of an inhibitor of the synaptic vesicle acetylcholine transport system on quantal neurotransmitter release: an electrophysiological study. Lupa, M.T. Brain Res. (1988) [Pubmed]
  8. Actions of vesamicol on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor. Buckingham, S.D., Lummis, S.C., Balk, M.L., Schroeder, M., Sattelle, D.B. J. Exp. Biol. (1993) [Pubmed]
  9. The nature and origin of calcium-insensitive miniature end-plate potentials at rodent neuromuscular junctions. Lupa, M.T., Tabti, N., Thesleff, S., Vyskocil, F., Yu, S.P. J. Physiol. (Lond.) (1986) [Pubmed]
  10. Inhibition of neurotransmitter and hormone transport into secretory vesicles by 2-(4-phenylpiperidino)cyclohexanol and 2-bromo-alpha-ergocryptine: both compounds act as uncouplers and dissipate the electrochemical gradient of protons. Moriyama, Y., Amakatsu, K., Yamada, H., Park, M.Y., Futai, M. Arch. Biochem. Biophys. (1991) [Pubmed]
  11. The effect of 2-(4-phenylpiperidino)cyclohexanol (AH-5183), tityustoxin and ouabain on the release of acetylcholine and its mobilization from cytoplasmic and vesicular pools of rat brain cortical slices. Prado, M.A., Santos, T.M., Gomez, M.V. Neurosci. Lett. (1990) [Pubmed]
  12. [3H]2-(4-phenylpiperidino)cyclohexanol (AH5183) binding to synaptosomes and subcellular fractions obtained from rat brain. Suzuki, T., Kashima, Y., Fujimoto, K., Kawashima, K. Neurosci. Lett. (1993) [Pubmed]
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